ID A0A220VH89_9GAMM Unreviewed; 594 AA.
AC A0A220VH89;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Sodium:proton antiporter {ECO:0000313|EMBL:ASK79727.1};
GN ORFNames=CF386_11835 {ECO:0000313|EMBL:ASK79727.1};
OS Paraphotobacterium marinum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Paraphotobacterium.
OX NCBI_TaxID=1755811 {ECO:0000313|EMBL:ASK79727.1, ECO:0000313|Proteomes:UP000242175};
RN [1] {ECO:0000313|EMBL:ASK79727.1, ECO:0000313|Proteomes:UP000242175}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NSCS20N07D {ECO:0000313|EMBL:ASK79727.1,
RC ECO:0000313|Proteomes:UP000242175};
RX PubMed=27154455; DOI=10.1099/ijsem.0.001142;
RA Huang Z., Dong C., Shao Z.;
RT "Paraphotobacterium marinum gen. nov., sp. nov., a member of the family
RT Vibrionaceae, isolated from surface seawater.";
RL Int. J. Syst. Evol. Microbiol. 66:3050-3056(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP022356; ASK79727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A220VH89; -.
DR KEGG; pmai:CF386_11835; -.
DR OrthoDB; 570124at2; -.
DR Proteomes; UP000242175; Chromosome small.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242175};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 398..502
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 594 AA; 66136 MW; 58B2DB549E185E14 CRC64;
MSLENISLIL SSLALVGFLC QWVSWKFQVP SILLLLLLGL FLGPFSNILQ PDLLFGDLLF
PVVSLSVAII LFEGSLTLNF KELKGAGQTV RSMVSWGAII SWILTSCATH YILNFSWSLA
ILFGSLTVVT GPTVIAPLLR TVKPQSNLAK ILRWEGILID PIGALFVVII YEFIMSSSEL
HSLKVFSIII MIGIFMGIIS GIILAHILRK NYLPEYLHSF AVLTFVLMVF SLSNMIENEA
GLLSVTILGM WLANTKEVDI KHILHFKENL TILLISGLFL ILASRIQLSD FSTLGWNALF
VLIFIQFISR PLSIFISTIR STLNFKEKLF LSWVAPRGIV AAAISALFSI KLVSIQVENA
ELIVPLTFLV IIGTVVLQSI TARPIAKLLG VAEPSPHGFL VIGANEFARM LALAIKKYDY
KVILTDSNWD YIRDARMAGF ETYYGNPTSS HADEYLNLIG IGSAISVTSD EHFNLIASNK
FIDNFSKNNV YALIEKKELS EYKNKHKSAS QYRGQFMLNN LSYQKILTAI KKGAAIRHTK
ISETFTVENY LENYVNKVIP LFIVDKENNI KILGLNDILT TEPGSTIVAL INDK
//
