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Database: UniProt
Entry: A0A221P0A8_9ACTN
LinkDB: A0A221P0A8_9ACTN
Original site: A0A221P0A8_9ACTN 
ID   A0A221P0A8_9ACTN        Unreviewed;       310 AA.
AC   A0A221P0A8;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   11-DEC-2019, entry version 8.
DE   SubName: Full=Prephenate dehydratase {ECO:0000313|EMBL:ASN25506.1};
GN   ORFNames=LK07_17340 {ECO:0000313|EMBL:ASN25506.1};
OS   Streptomyces pluripotens.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1355015 {ECO:0000313|EMBL:ASN25506.1, ECO:0000313|Proteomes:UP000031501};
RN   [1] {ECO:0000313|EMBL:ASN25506.1, ECO:0000313|Proteomes:UP000031501}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MUSC 137 {ECO:0000313|EMBL:ASN25506.1,
RC   ECO:0000313|Proteomes:UP000031501};
RA   Ser H.-L., Lee L.-H.;
RT   "Genome sequence of Streptomyces pluripotens MUSC 137T.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP022433; ASN25506.1; -; Genomic_DNA.
DR   RefSeq; WP_039654921.1; NZ_CP022433.1.
DR   KEGG; splu:LK06_016185; -.
DR   KO; K04518; -.
DR   OrthoDB; 1280729at2; -.
DR   Proteomes; UP000031501; Chromosome.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:InterPro.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000031501}.
FT   DOMAIN          4..182
FT                   /note="Prephenate dehydratase"
FT                   /evidence="ECO:0000259|PROSITE:PS51171"
FT   DOMAIN          197..274
FT                   /note="ACT"
FT                   /evidence="ECO:0000259|PROSITE:PS51671"
FT   SITE            175
FT                   /note="Essential for prephenate dehydratase activity"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001500-2"
SQ   SEQUENCE   310 AA;  33478 MW;  D64CA78156E3D4DB CRC64;
     MPASYAYLGP EGTFTEVALR TLPEAATRKL VPYVSVQSAL DAVRAGDAEA AFVPIENSVE
     GGITTTLDEL VAGEPLMIYR EVLLSITFAL LVRPGTKLAD VKTVSAHPAA QPQVRNWLRK
     HLPDAVWESA ASNADAARLV QEGRYDAAFA GEFAAARYGL EALETGIHDA ENAQTRFVLV
     GRPARPAAPS GADKTSVVLW QRDDHPGALR DLLGEFASRG INLMLLQSRP TGAGIGHYCF
     CIDAEGHIAD RRMAEALMGL KRICLQVRFL GSYPRADITP DAARPKFPGT SDEEFMAAAD
     WVARCQDGRF
//
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