ID   A0A221R3E0_9MICC        Unreviewed;       379 AA.
AC   A0A221R3E0;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Mannose-1-phosphate guanylyltransferase {ECO:0000313|EMBL:ASN51384.1};
GN   ORFNames=CGQ25_04235 {ECO:0000313|EMBL:ASN51384.1};
OS   Sinomonas sp. R1AF57.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Sinomonas.
OX   NCBI_TaxID=2020377 {ECO:0000313|EMBL:ASN51384.1, ECO:0000313|Proteomes:UP000199767};
RN   [1] {ECO:0000313|EMBL:ASN51384.1, ECO:0000313|Proteomes:UP000199767}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R1AF57 {ECO:0000313|EMBL:ASN51384.1,
RC   ECO:0000313|Proteomes:UP000199767};
RA   Sastre D.E., Santos L., Kagohara E., Andrade L.H.;
RT   "Draft Genome Sequence of Sinomonas sp., Isolated from Brazilian Amazon
RT   Soils with Potential for Applications in Biocatalysis.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP022463; ASN51384.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A221R3E0; -.
DR   Proteomes; UP000199767; Chromosome.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0005976; P:polysaccharide metabolic process; IEA:InterPro.
DR   InterPro; IPR001538; Man6P_isomerase-2_C.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR   PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR   Pfam; PF01050; MannoseP_isomer; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF159283; Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000313|EMBL:ASN51384.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199767};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ASN51384.1}.
FT   DOMAIN          17..302
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
FT   DOMAIN          338..376
FT                   /note="Mannose-6-phosphate isomerase type II C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01050"
SQ   SEQUENCE   379 AA;  39762 MW;  D587DDE14B7A2A90 CRC64;
     MKLSSAAPGS VLDRFVAVIP AGGVGTRLWP LSRAAAPKFL HDLTGSGSTL IRATYDRLAP
     LANGRFLVVT GLAHEAAVCR QIPELDPSDV VLESEPKDSG AAIGLAAAIL HRRSPDIIMG
     SFAADQVISP DDVFQAAVRE AVYTAASGER GKIVTIGIEP THPSTGFGYI RGGEALDVEG
     APSARAVAEF VEKPNREVAE KYLASGEYLW NAGMFVAPVK LMLEHLAANQ PVLFEGLTEI
     AAAWDTPDRD EVTARVWPTL PKIAIDYAVA EPAAAAGDVA VVPGAFRWDD VGDFAAIGRL
     NSAREEDAVT VLGEGARVFT EDASGIVVSD TKRVIALIGI EDVVIVDTPD ALLVTTKEHA
     QKVKNAVAGL KASGDTDVL
//