ID A0A221R480_9MICC Unreviewed; 459 AA.
AC A0A221R480;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=C4-dicarboxylate transporter DctA {ECO:0000313|EMBL:ASN51727.1};
GN ORFNames=CGQ25_06295 {ECO:0000313|EMBL:ASN51727.1};
OS Sinomonas sp. R1AF57.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Sinomonas.
OX NCBI_TaxID=2020377 {ECO:0000313|EMBL:ASN51727.1, ECO:0000313|Proteomes:UP000199767};
RN [1] {ECO:0000313|EMBL:ASN51727.1, ECO:0000313|Proteomes:UP000199767}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R1AF57 {ECO:0000313|EMBL:ASN51727.1,
RC ECO:0000313|Proteomes:UP000199767};
RA Sastre D.E., Santos L., Kagohara E., Andrade L.H.;
RT "Draft Genome Sequence of Sinomonas sp., Isolated from Brazilian Amazon
RT Soils with Potential for Applications in Biocatalysis.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP022463; ASN51727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A221R480; -.
DR Proteomes; UP000199767; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0046942; P:carboxylic acid transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF1; AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199767};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 434..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 459 AA; 47896 MW; BDC6AC2FF38A781C CRC64;
MATSPTAPER APAKKPADRT HVLYIAVIVA VVLGVVVGLL FPGKDGFAAD LKPLGDGFVA
LIKMMIAPVI FCTIVLGIGS IAKAATVGKV GGLALLYFMV MSTFALAIGL VVGNFIHPGE
GLNLKDATYK ATESADTTNF LLGIIPKTLV SSLTSGEILQ TLFVALLVGF ALQRMGKTGA
LLLEFIRQAQ VLVFRILIMI MWLAPIGAFG AIAAVVGATG WKAVLSLLTL MVAFYITCIL
FIVFILGTIL KVVSGVNIFK LMKYLGREYL IIVSTSSSEA ALPRLIAKME HLGVSKPVVG
VTVPTGYSFN LDGTAIYLTM ASLFIATAMG QPLALGEQIG LLVFMIIASK GAAGVSGAGL
ATLAGGLQAH APQLVGGVSF IVGIDRFMSE ARALTNFTGN AVATVLMGTW TREIDTDRVG
EVLSGRRPFD ETTMLAGHGH GGEPESEDVV GAPGEPART
//
