ID A0A221R8J2_9MICC Unreviewed; 465 AA.
AC A0A221R8J2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=MBL fold metallo-hydrolase {ECO:0000313|EMBL:ASN53214.1};
GN ORFNames=CGQ25_14850 {ECO:0000313|EMBL:ASN53214.1};
OS Sinomonas sp. R1AF57.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Sinomonas.
OX NCBI_TaxID=2020377 {ECO:0000313|EMBL:ASN53214.1, ECO:0000313|Proteomes:UP000199767};
RN [1] {ECO:0000313|EMBL:ASN53214.1, ECO:0000313|Proteomes:UP000199767}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R1AF57 {ECO:0000313|EMBL:ASN53214.1,
RC ECO:0000313|Proteomes:UP000199767};
RA Sastre D.E., Santos L., Kagohara E., Andrade L.H.;
RT "Draft Genome Sequence of Sinomonas sp., Isolated from Brazilian Amazon
RT Soils with Potential for Applications in Biocatalysis.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP022463; ASN53214.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A221R8J2; -.
DR Proteomes; UP000199767; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ASN53214.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199767}.
FT DOMAIN 19..246
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 257..376
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 465 AA; 50730 MW; 6D24899D046A4BFD CRC64;
MTHDGGARLS FWGATDTVTG SRYLLEHGGQ RILVDCGLFQ GYKKLRERNR APLPLAPSSI
DAVVLTHAHL DHSGYVPALV RDGFRGPVYA TPGTAELCTL LLPDSGHLLE EEAETARLRG
SSRHHPPRPL YTATDAVEAL RSFRPHPFRE PLEIGDGISV RFVPAGHILG ASQVRVALGA
GGSELTVHFT GDLGRRDDPL MNPPEQLEPA QVLVAESTYG DRAHPAESAE DALGDVVRRV
AKLGGVVVIA AFAVGRAETL MLHLARLRRK GKIPDIPVYL NSPMAVDASE MYRDHRDEHR
IDEREFREMY NLPTMVREPD DSKLLNLRGG PMVIISASGM LTGGRVLHHV EAYGGEAKNA
IVLSGYQAGG TRGASLLDGA GSLRIYGRDV PIRAEVVSLE NLSAHADADE ILRWMGACST
APRMVYVTHG EPEASDALRR RIQHELGWRA RVPEHLEQVD LADPR
//
