ID A0A221RA68_9MICC Unreviewed; 500 AA.
AC A0A221RA68;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN Name=mmsA {ECO:0000313|EMBL:ASN52995.1};
GN ORFNames=CGQ25_13590 {ECO:0000313|EMBL:ASN52995.1};
OS Sinomonas sp. R1AF57.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Sinomonas.
OX NCBI_TaxID=2020377 {ECO:0000313|EMBL:ASN52995.1, ECO:0000313|Proteomes:UP000199767};
RN [1] {ECO:0000313|EMBL:ASN52995.1, ECO:0000313|Proteomes:UP000199767}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R1AF57 {ECO:0000313|EMBL:ASN52995.1,
RC ECO:0000313|Proteomes:UP000199767};
RA Sastre D.E., Santos L., Kagohara E., Andrade L.H.;
RT "Draft Genome Sequence of Sinomonas sp., Isolated from Brazilian Amazon
RT Soils with Potential for Applications in Biocatalysis.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP022463; ASN52995.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A221RA68; -.
DR Proteomes; UP000199767; Chromosome.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000199767}.
FT DOMAIN 17..480
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 500 AA; 53023 MW; B6B8D07A4798E3E7 CRC64;
MVRDLHHYIG GARVDGTSGR FGDVYDPCRG EVQARVPLAS ADEVRGAIAS AEKGQPEWAA
MNPQRRGRIL LKFVDLVNEN MDELARLLAS EHGKTFADAK GDLQRGLEVV EFSAGAAPHL
LKGEFSDSVA TGVDVHSLRK PLGVVAGISP FNFPAMIPLW QAGPALAAGN AFVCKPSERD
PSVPLRLAEL LTEAGLPDGV FNVVNGDKEA VDTLLEDPRV KAIGFVGSTP IAQYIYETAA
KNGKRAQCFG GAKNHMVVLP DADLDMAADA LIGAGYGSAG ERCMAISVAV PVGEETADAL
VGKLRERIAG LRVGASLDKD VDFGPVVAAS AKERIEGYIA AGAEEGAELV VDGRGHAVEG
YEGGFWVGPT LFDRVTKDMS VYRDEIFGPV LSVVRAADYD EALRLCSEHE FGNGVAIFTR
DGDAARDFAS RVEVGMVGVN VPIPVPIAYY TFGGWKASGF GDLNQHGPDA FRFFTKTKTV
TTRWPSGVRQ GASFVMPAGS
//
