ID A0A221SYY8_9DEIO Unreviewed; 346 AA.
AC A0A221SYY8;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Topoisomerase I {ECO:0000313|EMBL:ASN81854.1};
GN ORFNames=DFI_13420 {ECO:0000313|EMBL:ASN81854.1};
OS Deinococcus ficus.
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=317577 {ECO:0000313|EMBL:ASN81854.1, ECO:0000313|Proteomes:UP000259030};
RN [1] {ECO:0000313|EMBL:ASN81854.1, ECO:0000313|Proteomes:UP000259030}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-FR2-10 {ECO:0000313|EMBL:ASN81854.1,
RC ECO:0000313|Proteomes:UP000259030};
RA Wu K.-M., Liao T.-L., Liu Y.-M., Young C.-C., Tsai S.-F.;
RT "The complete genome sequence of Deinococcus ficus isolated from the
RT rhizosphere of the Ficus religiosa L. in Taiwan.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP021081; ASN81854.1; -; Genomic_DNA.
DR RefSeq; WP_027464237.1; NZ_CP021081.1.
DR AlphaFoldDB; A0A221SYY8; -.
DR STRING; 317577.GCA_000419625_01239; -.
DR KEGG; dfc:DFI_13420; -.
DR Proteomes; UP000259030; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003917; F:DNA topoisomerase type I (single strand cut, ATP-independent) activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00659; Topo_IB_C; 1.
DR Gene3D; 1.10.132.120; -; 1.
DR Gene3D; 3.30.66.10; DNA topoisomerase I domain; 1.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR035447; DNA_topo_I_N_sf.
DR InterPro; IPR049331; Top1B_N_bact.
DR InterPro; IPR014711; TopoI_cat_a-hlx-sub_euk.
DR InterPro; IPR013500; TopoI_cat_euk.
DR Pfam; PF21338; Top1B_N_bact; 1.
DR Pfam; PF01028; Topoisom_I; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR SUPFAM; SSF55869; DNA topoisomerase I domain; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000313|EMBL:ASN81854.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000259030}.
FT DOMAIN 23..70
FT /note="DNA topoisomerase IB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21338"
FT DOMAIN 89..286
FT /note="DNA topoisomerase I catalytic core eukaryotic-type"
FT /evidence="ECO:0000259|Pfam:PF01028"
SQ SEQUENCE 346 AA; 38590 MW; 31C6DEAC5579F14C CRC64;
MPSRTELLAA EYLRREGHDP KAFRYFTPDG REYRNRAGLA RIAALAVPPA YQDVYVSPDP
DAELQAFGRD AAGRLQYRYH PDFVQAGALK KWQRLSRFAG VLPDLRAATT ADLRSAGLPP
RKVTALMTRL LHVARFRVGS DAYAQHNRTY GLSTLRQRHV VVEGSTVTFR FRGKHGISQH
KATTDRTLAA NISKLLELPG PWLFQAADDA AGGRRRVRAP ELNTYLREVI GPFTAKDFRT
WGGTLLAAEF LAEAGTADTE RSAKRTLVEC VKYVADDLGN TPAVTRGSYI CPVIFDRYLD
GKVLDDYEPR TARQEAALDG LTRSEAALKR MLDSERALRT RARKAA
//
