ID   A0A221T2R8_9DEIO        Unreviewed;       690 AA.
AC   A0A221T2R8;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=DFI_18535 {ECO:0000313|EMBL:ASN83198.1};
OS   Deinococcus ficus.
OG   Plasmid pdfi3 {ECO:0000313|Proteomes:UP000259030}.
OC   Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=317577 {ECO:0000313|EMBL:ASN83198.1, ECO:0000313|Proteomes:UP000259030};
RN   [1] {ECO:0000313|EMBL:ASN83198.1, ECO:0000313|Proteomes:UP000259030}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC-FR2-10 {ECO:0000313|EMBL:ASN83198.1,
RC   ECO:0000313|Proteomes:UP000259030};
RC   PLASMID=pdfi3 {ECO:0000313|Proteomes:UP000259030};
RA   Wu K.-M., Liao T.-L., Liu Y.-M., Young C.-C., Tsai S.-F.;
RT   "The complete genome sequence of Deinococcus ficus isolated from the
RT   rhizosphere of the Ficus religiosa L. in Taiwan.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; CP021084; ASN83198.1; -; Genomic_DNA.
DR   RefSeq; WP_027464340.1; NZ_CP021084.1.
DR   AlphaFoldDB; A0A221T2R8; -.
DR   KEGG; dfc:DFI_18535; -.
DR   Proteomes; UP000259030; Plasmid pdfi3.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Plasmid {ECO:0000313|EMBL:ASN83198.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000259030}.
FT   DOMAIN          10..278
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   REGION          496..534
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        500..527
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         31..38
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   690 AA;  76169 MW;  48BD54D2D07F7FD6 CRC64;
     MTSHRLNQPT PEQRDFLDAV AHTGDHLFLR ATAGSGKTTT LVEAAWSLPV RQRTVYFAYN
     RHAVQDLRGR LPGDVQARTL HAHGLKTLGT CVIDGQKAST LCAGQAQELA SDPGVVQVLT
     RVLLKAFNAM RELQLPPGTP DLALEWAEHR PPGVPDVSWQ RRFSTALSQI ARAGVEQYET
     TRTIDYTDML WLPLQTGQGR SSVAHAIVDE AQDLTPLRWA YLMHVTGQRG KQPGRIIACG
     DPEQSIYQYS GAEPGGMQRQ ADALGARVYP LSISWRCPAL VVREAQRCST FIRAAPTARQ
     GAVRRVLSTH HDYRTTQAVL CRTNAPLIVL ALQLHRDGLR VSLGGEDLSA QLVKAARELP
     DPYTEADVER LEQLTPPPKT ALQALHADLR VAAAQLARET LRGRSQATRQ ALSRLVDQLC
     QSSPGTVYLS TIHRAKGMEW DDVTVLQPEL MPLPYGTAEE ERCVEFVAIT RARRRLTYAL
     GPEAWDAYET ELSSAPLPAA ARPPKRPTPP PKRPAPANPP PRAPDGSEGP PRVITVALPD
     DAPSCVREWN IFTGQDPVPA MALRQALQRV ARAKRPQLSV WAAATLERVQ RLPGNAAVLI
     DHDRLHQAEQ AVTASTISIP AMPPRPPRPH RQLLITEHSL ARWKYGEIEG ETDQLVTLTY
     RGARYTFDKT TCELSGQPFD PAQPYLHPDR
//