ID A0A221W6W4_9PSEU Unreviewed; 353 AA.
AC A0A221W6W4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=L-threonine 3-dehydrogenase {ECO:0000313|EMBL:ASO21309.1};
DE EC=1.1.1.103 {ECO:0000313|EMBL:ASO21309.1};
DE SubName: Full=Threonine dehydrogenase-like Zn-dependent dehydrogenase {ECO:0000313|EMBL:MBB5921242.1};
GN Name=tdh2 {ECO:0000313|EMBL:ASO21309.1};
GN ORFNames=AHOG_18420 {ECO:0000313|EMBL:ASO21309.1}, FHR81_002280
GN {ECO:0000313|EMBL:MBB5921242.1};
OS Actinoalloteichus hoggarensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinoalloteichus.
OX NCBI_TaxID=1470176 {ECO:0000313|EMBL:ASO21309.1, ECO:0000313|Proteomes:UP000204221};
RN [1] {ECO:0000313|EMBL:ASO21309.1, ECO:0000313|Proteomes:UP000204221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45943 {ECO:0000313|EMBL:ASO21309.1,
RC ECO:0000313|Proteomes:UP000204221};
RA Ruckert C., Nouioui I., Willmese J., van Wezel G., Klenk H.-P.,
RA Kalinowski J., Zotchev S.B.;
RT "Complete genome sequence of Actinoalloteichus hoggarensis DSM 45943, type
RT strain of Actinoalloteichus hoggarensis.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBB5921242.1, ECO:0000313|Proteomes:UP000541573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 8639 {ECO:0000313|EMBL:MBB5921242.1,
RC ECO:0000313|Proteomes:UP000541573};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CP022521; ASO21309.1; -; Genomic_DNA.
DR EMBL; JACHJM010000003; MBB5921242.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A221W6W4; -.
DR KEGG; ahg:AHOG_18420; -.
DR OrthoDB; 9797931at2; -.
DR Proteomes; UP000204221; Chromosome.
DR Proteomes; UP000541573; Unassembled WGS sequence.
DR GO; GO:0008743; F:L-threonine 3-dehydrogenase activity; IEA:UniProtKB-EC.
DR CDD; cd08230; glucose_DH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR031640; Glu_dehyd_C.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF16912; Glu_dehyd_C; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ASO21309.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000204221}.
FT DOMAIN 26..137
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 146..348
FT /note="Glucose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16912"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 353 AA; 37823 MW; 76299EBC3023C415 CRC64;
MRALTVMPGE RDSLRVDEVD DPTPGPGELL VDGLAVGVCG TDREIVDAQF GEPVPGRSRL
IIGHESLGRV RRAPEGTDFA EGDLVVGVVR RPDPEPCGAC ARGYFDMCRN GRYTERGIKG
LDGYASESWT LEADYAVRLD PRLSGVGMLL EPTSVVAKAW DQIERIGARS WFEPETVLVT
GAGPIGLLAA LIGVQRGLDV HVLDRVVGGP KVDLVRDLGA TYHHDSVTDF GRRLRPDIVI
EATGVDQLVC ESMAVTAAYG IVCLTGVSSP GRVLPTDLGS LNRSIVLEND AVFGSVNANL
THYTAAADAL AAADLGWLDR LVSRRVPLTR FHEAFEHHQD DVKVIIDLTA AAG
//
