ID A0A222P345_9GAMM Unreviewed; 453 AA.
AC A0A222P345;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Ribonuclease {ECO:0000313|EMBL:ASQ46252.1};
DE EC=3.1.-.- {ECO:0000313|EMBL:ASQ46252.1};
GN ORFNames=clem_08500 {ECO:0000313|EMBL:ASQ46252.1};
OS Legionella clemsonensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=1867846 {ECO:0000313|EMBL:ASQ46252.1, ECO:0000313|Proteomes:UP000201728};
RN [1] {ECO:0000313|Proteomes:UP000201728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC-D5610 {ECO:0000313|Proteomes:UP000201728};
RA Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP016397; ASQ46252.1; -; Genomic_DNA.
DR RefSeq; WP_014843650.1; NZ_CP016397.1.
DR AlphaFoldDB; A0A222P345; -.
DR KEGG; lcd:clem_08500; -.
DR OrthoDB; 9803916at2; -.
DR Proteomes; UP000201728; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ASQ46252.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000201728}.
FT DOMAIN 13..223
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 247..367
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 453 AA; 50465 MW; C4D86B7DADC8C097 CRC64;
MKLTFLGATE TVTGSKYLLT VGSKKILIDC GLFQGYKELR LRNWAPLPID PHDIDAVIIT
HAHIDHTGYL PLLVKNGFQG KIYATPGTKA LCSILLPDSG HLQEEEARLA NKYGFSKHQP
ALPLYTEKEA HTALQYFETI DFDTPHQLFH DFSFVYHRAG HIVGAAMVKI KTQKGSIVFT
GDIGRPYDPV MKAPAFIQET DYLVMESTYG DRLHDATDPL PQMAQVINQT VKRGGSVVIP
AFAVGRAQSL LYFIYELKRQ GQITKDLPVF LDSPMAIDAT HLLCTYKEDH HLTAEQCRGL
CHVATYVNTP EESKEIDRHH MPQIIIAASG MAQGGRILHH LKAFAPNPKN TLLFTGFQAG
GTRGARIVNG EKQVKIHGSF IPIQAKVVVM SSTSAHADYP ELLEWLTHLT NPPKKVFITH
GEPHSAQSLK QKIEKQLGFS CTIPSYLQTE ELW
//
