ID A0A222VPP1_9PSEU Unreviewed; 557 AA.
AC A0A222VPP1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Aspartate-alanine antiporter {ECO:0000313|EMBL:SDC28341.1};
GN ORFNames=DES30_101211 {ECO:0000313|EMBL:PWV84194.1},
GN SAMN05421630_1011126 {ECO:0000313|EMBL:SDC28341.1};
OS Prauserella marina.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Prauserella.
OX NCBI_TaxID=530584 {ECO:0000313|EMBL:SDC28341.1, ECO:0000313|Proteomes:UP000199494};
RN [1] {ECO:0000313|EMBL:SDC28341.1, ECO:0000313|Proteomes:UP000199494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5506 {ECO:0000313|EMBL:SDC28341.1,
RC ECO:0000313|Proteomes:UP000199494};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PWV84194.1, ECO:0000313|Proteomes:UP000246674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45268 {ECO:0000313|EMBL:PWV84194.1,
RC ECO:0000313|Proteomes:UP000246674};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC {ECO:0000256|ARBA:ARBA00009854}.
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DR EMBL; QGTN01000001; PWV84194.1; -; Genomic_DNA.
DR EMBL; FMZE01000001; SDC28341.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A222VPP1; -.
DR STRING; 530584.SAMN05421630_1011126; -.
DR KEGG; pmad:BAY61_13705; -.
DR OrthoDB; 5166626at2; -.
DR Proteomes; UP000199494; Unassembled WGS sequence.
DR Proteomes; UP000246674; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR022457; Asp_Ala_antiprt.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR006512; YidE_YbjL.
DR NCBIfam; TIGR03802; Asp_Ala_antiprt; 1.
DR NCBIfam; TIGR01625; YidE_YbjL_dupl; 1.
DR PANTHER; PTHR30445:SF8; TRANSPORT PROTEIN YBJL-RELATED; 1.
DR PANTHER; PTHR30445; UNCHARACTERIZED; 1.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199494};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 530..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 204..285
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 557 AA; 57629 MW; B905420434DD9E4A CRC64;
MSILRERPEL ALFLCLALGY LIGKIRVGPI QLGGICGVLI VALLIGTQNV TVDSGVKTVA
FALFIFALGY VGGPQFFAHL NRSGLRFGVL SVIEVVCVVG IALTLAGAFD LDIGTASGIL
AGAATESAVV GTATEAIGKL GLPADQVSAL QGNVATAYTV CYLFGLVTIV LFTSQLAPLL
LRINLAVASR ELWSKTKGGD TSLADDEQPA LPSLVGRTYL VHAAAGRTIS GVEGDLNGGA
SIESVKRGKD ILHPAPDLTL REGDIVLVVG QRASAVEAGV EIGVETSSVP GLDTPLVVRD
VVLTSRKLHR ATVASVRRDN PELAEGGVYL TGIQRGDNDL PVARETELHR GDVVTLVGTR
AKVDRIVKDF GAKIRNDTAD YVYIGLGLSV GVLLGAITVR IGDVPMSLGT GGGCLISGLV
FGWIRSLHPT FGAFPPAAAQ TMKDLGLAVF IAVTGLAAGP HAWDLLKQYG ALLPLAGIGM
VLIPALLSIW VGRKLLKIEP PLLIGAIAGQ QCSTPGITAI TAVAKSTVPL LGYTITYTIS
NFLLPLTGPL LVGILGS
//
