ID A0A222W0S7_9PSEU Unreviewed; 377 AA.
AC A0A222W0S7;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=SAMN05421630_11229 {ECO:0000313|EMBL:SDD76081.1};
OS Prauserella marina.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Prauserella.
OX NCBI_TaxID=530584 {ECO:0000313|EMBL:SDD76081.1, ECO:0000313|Proteomes:UP000199494};
RN [1] {ECO:0000313|EMBL:SDD76081.1, ECO:0000313|Proteomes:UP000199494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5506 {ECO:0000313|EMBL:SDD76081.1,
RC ECO:0000313|Proteomes:UP000199494};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
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DR EMBL; FMZE01000012; SDD76081.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A222W0S7; -.
DR STRING; 530584.SAMN05421630_11229; -.
DR KEGG; pmad:BAY61_22295; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000199494; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000199494}.
FT DOMAIN 111..363
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT REGION 84..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 377 AA; 39442 MW; 9AC1E4F998E768D9 CRC64;
MTRRDASTIL GDYRPPRSFF ATESRTILCE GTAAHVHADN AVSLAERALA ALDSQGAPLV
VGAFPFHDKV GAALTIPETV EVGGGLPRSG ARGPQPPLVP PSRVRSLPGR AEHRAAVSAL
TDRIAATGLR KAVLARALDL EFAEPVPAEL ILRNLVRGNP GGYTFAVGDE PTLLGASPEL
LLSREGRKVR SHPLAGSARR CADPAEDKAN AAALVASAKD RAEHAMVTDA VAAALRPFCE
TLAVPPRPEL VATPTMWHLG TPIEGVLRDP GVTSLQLAAA LHPTPAVCGT PTDLAREVIG
ELEPFDRGHY AGMVGWMDVD GDGEWAVTIR CAELAGSAMR LYAGGGIVAG SDPVTELDET
SAKFQTLLRA MGLELTP
//
