ID A0A222Z4N3_9CAUD Unreviewed; 294 AA.
AC A0A222Z4N3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 13-SEP-2023, entry version 18.
DE RecName: Full=thymidylate synthase {ECO:0000256|ARBA:ARBA00011947};
DE EC=2.1.1.45 {ECO:0000256|ARBA:ARBA00011947};
GN ORFNames=OTK52_50 {ECO:0000313|EMBL:ASR79488.1};
OS Bacillus phage OTooleKemple52.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Herelleviridae; Bastillevirinae; Bastillevirus.
OX NCBI_TaxID=2024233 {ECO:0000313|EMBL:ASR79488.1, ECO:0000313|Proteomes:UP000224476};
RN [1] {ECO:0000313|Proteomes:UP000224476}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Raymond T.O., Adhikari S., Alickovic L., Culpepper R., Khella F.,
RA Leath A.J., Mcgill J., Ramaswamy A., Raynor J., Sainani J., Shah R.K.,
RA Soyars C., Varilla Z.E., Yonas M., Garlena R.A., Russell D.A., Barlow R.M.,
RA Johnson A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thymidylate synthase family.
CC {ECO:0000256|ARBA:ARBA00009972}.
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DR EMBL; MF288921; ASR79488.1; -; Genomic_DNA.
DR Proteomes; UP000224476; Genome.
DR GO; GO:0004799; F:thymidylate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd00351; TS_Pyrimidine_HMase; 1.
DR Gene3D; 3.30.572.10; Thymidylate synthase/dCMP hydroxymethylase domain; 1.
DR HAMAP; MF_00008; Thymidy_synth_bact; 1.
DR InterPro; IPR045097; Thymidate_synth/dCMP_Mease.
DR InterPro; IPR023451; Thymidate_synth/dCMP_Mease_dom.
DR InterPro; IPR036926; Thymidate_synth/dCMP_Mease_sf.
DR InterPro; IPR000398; Thymidylate_synthase.
DR NCBIfam; TIGR03284; thym_sym; 1.
DR PANTHER; PTHR11548:SF9; THYMIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11548; THYMIDYLATE SYNTHASE 1; 1.
DR Pfam; PF00303; Thymidylat_synt; 1.
DR PRINTS; PR00108; THYMDSNTHASE.
DR SUPFAM; SSF55831; Thymidylate synthase/dCMP hydroxymethylase; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 7..287
FT /note="Thymidylate synthase/dCMP hydroxymethylase"
FT /evidence="ECO:0000259|Pfam:PF00303"
SQ SEQUENCE 294 AA; 33898 MW; CDAA76CEA1ED7344 CRC64;
MNNVDKQVLD LYDYILKHGE VKSDRTGTGT LSIFDYTMRF DMSEGFPLLT TKHVAFRLVA
EELLWFLKGD TNLKTLIDKN VNIWTPDGYR WYKELGGTLS KEEFVEFVKE NGFDLGRIYG
AQWTDWNGEG YNQIKEVIAE IKRNPSSRRL YVSAWHPTDF KKAALPCCHH AFQLYVHNNG
KLDLKFFMRS NDGFLGLAFN IASYALLLHL IALECGLEVG SLIYNGGDVH LYLNHIEQAK
EQLLNEPRKL PKLVIKNKKD NLEDYDIEDF EIVDYNPHKA IKAPVSVGLK EEVK
//
