ID A0A223CWP9_9BACL Unreviewed; 255 AA.
AC A0A223CWP9;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 13-SEP-2023, entry version 14.
DE RecName: Full=Cobalt transport protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE Short=ECF transporter S component CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
GN Name=cbiM {ECO:0000256|HAMAP-Rule:MF_01462};
GN ORFNames=CIG75_01060 {ECO:0000313|EMBL:ASS73702.1};
OS Tumebacillus algifaecis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Tumebacillus.
OX NCBI_TaxID=1214604 {ECO:0000313|EMBL:ASS73702.1, ECO:0000313|Proteomes:UP000214688};
RN [1] {ECO:0000313|EMBL:ASS73702.1, ECO:0000313|Proteomes:UP000214688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=THMBR28 {ECO:0000313|EMBL:ASS73702.1,
RC ECO:0000313|Proteomes:UP000214688};
RX PubMed=25858243; DOI=10.1099/ijs.0.000240;
RA Wu Y.F., Zhang B., Xing P., Wu Q.L., Liu S.J.;
RT "Tumebacillus algifaecis sp. nov., isolated from decomposing algal scum.";
RL Int. J. Syst. Evol. Microbiol. 65:2194-2198(2015).
CC -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC CbiMNOQ involved in cobalt import. {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC (S components, CbiM and CbiN) of unknown stoichimetry.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01462};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01462}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CbiM family. {ECO:0000256|HAMAP-
CC Rule:MF_01462}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP022657; ASS73702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A223CWP9; -.
DR KEGG; tab:CIG75_01060; -.
DR OrthoDB; 9809846at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000214688; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.1760.20; -; 1.
DR HAMAP; MF_01462; CbiM; 1.
DR InterPro; IPR018024; CbiM.
DR InterPro; IPR002751; CbiM/NikMN.
DR NCBIfam; TIGR00123; cbiM; 1.
DR PANTHER; PTHR43627; -; 1.
DR PANTHER; PTHR43627:SF1; COBALT TRANSPORT PROTEIN CBIM; 1.
DR Pfam; PF01891; CbiM; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285, ECO:0000256|HAMAP-Rule:MF_01462};
KW Cobalt transport {ECO:0000256|ARBA:ARBA00022426, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01462};
KW Reference proteome {ECO:0000313|Proteomes:UP000214688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01462}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 44..62
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 113..131
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 138..157
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 169..190
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 211..234
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
SQ SEQUENCE 255 AA; 27593 MW; 34004AEB097CD0F0 CRC64;
MKKVRKIAPL LLTFALTIYL YLNASESAYA MHIMEGFLSP GWSLFWWAVF LPFFVLGLRA
LVKITKENPE LKLMIGMAGA FTFVLSALKL PSVTGSSSHP TGVGLGTVMF GPLPMSVLGS
IVLLFQALLL AHGGLTTLGA NAFSMAVAGP FVGYFMYKLL MNTTGQQKIA IFAAAMFADL
STYVVTSLQL SLAFPSETGG ILASFAKFGS IFALTQIPLA ISEGLLTVLV WNWLQKYNTE
ELSLLNRKMK GAIRS
//
