ID A0A223CXI6_9BACL Unreviewed; 1432 AA.
AC A0A223CXI6;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=HTH luxR-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CIG75_02880 {ECO:0000313|EMBL:ASS74028.1};
OS Tumebacillus algifaecis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Tumebacillus.
OX NCBI_TaxID=1214604 {ECO:0000313|EMBL:ASS74028.1, ECO:0000313|Proteomes:UP000214688};
RN [1] {ECO:0000313|EMBL:ASS74028.1, ECO:0000313|Proteomes:UP000214688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=THMBR28 {ECO:0000313|EMBL:ASS74028.1,
RC ECO:0000313|Proteomes:UP000214688};
RX PubMed=25858243; DOI=10.1099/ijs.0.000240;
RA Wu Y.F., Zhang B., Xing P., Wu Q.L., Liu S.J.;
RT "Tumebacillus algifaecis sp. nov., isolated from decomposing algal scum.";
RL Int. J. Syst. Evol. Microbiol. 65:2194-2198(2015).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP022657; ASS74028.1; -; Genomic_DNA.
DR KEGG; tab:CIG75_02880; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000214688; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000214688};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..183
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1363..1428
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 1432 AA; 162171 MW; 31D81A582E507C0C CRC64;
MFTNSEKQLT EWLPMAPFEE KAFLQIAITL SEMVYRIHRQ NVRIGGLSPA NVRMSADRTL
AELSETVEMH DIYQAPEQTG RINRTPDGRS DLYSLGVIFY ELLTGVLPFQ AQGETNWSYL
HISAPPRPLG EMRPELEGPL QDIVLKLLAK SPEDRYQSAY GLLADLKQCA RMLEQNGVLM
PFLIGRVDEI REFRLPHNLF GRDEQMQWLV AGFELAAAGK SVFRSIRGVA GIGKTALINQ
FQETVARRGG RFVGGKGDPR DQDRPYEPVL QALRQWIEEL WSEPTDTVAS LKERLNARLG
EEAQTIVACW PEACALLGDP AGEAPACGPA VAARFGELLP EMIGCMAEGE QSLVLYLDDL
QWADVSTIRL LHRLARDEEI KGLMVIGASR EEADSNWIAD TADQTELPPL LYEDVRLWVS
SVLHEDTARA RLLARSMYLQ TQGNPRSLRL LLENWRNEKK LIYDEKQHRW MWDAEVTKRM
SESEESIRLV KAGFSRLSEE TRAMLAIAAA IGPCFPPEML AEVSGHSLEQ TLHLLQAAER
EGMICYEEQA KDRRGEERLY LFLHDQVWQM ADSIYADRRA DWHLKIGRLL QRQNSNWHDD
ALYETIDHLN LGMANMSDGE RAELAWHNYR AGSKAISSIQ YAKAKRYFET GLQLVESEVF
ESGSLVCKLT IELIECEHIC GNIERAQSLL RRVMIHKQKL NLEDRIRVYT YLIHLATYDQ
NDKAVQTGRE ALAELGWKLP EKVSTATVIK EVLLTQAVLY RMRDKFDRLP PNEEVEFKAV
SGLLVDLFTP LLIQDDKSLI ALYAKFIRYG AKKGINEPFV LLLSVYELLL QRGLPQFLEG
YCPIKLEHLQ ATSQLSQRFQ PKLPFMIGFS KQLENPIEAS IYLEKSLRLG VEITDPAFVN
LAIAMCLLNH CGDVHALSKL LAYMEREPRP FTVDRVLELI QVAKAYLAAL QDASLQDAFV
AIPDPDRMDR AQDEEDNFSC GCRLEVAYLS GKYKEAQYWA KRCRENELAP DLLQVRKQRL
YEALTFAACY VDATPDERKR TLRMLTKQMR LMRKRKGYLG ADSAAHLLIR AEWKRICGDR
QEAMQEYAAT IERARQEKQG LFEAISYERL AVCYQEAGSR TGVTISLMDA CTAYTVWGIT
AKAKQISSEH ADVSGYLSTP LEARATEMER EGQDLVRTDE NKVVDSPASL AEEDLLHQIV
RWSVKPNDPN LLESFLTATL RQAGADRGLV IRSLSGSFQI KAQTGSVNCE GAASTYSEAV
LRHVRMTGEA LMIDDAARSY FQKDPYIRQC APRSIICMPI VFPGNQPSDL LYLENTQVTG
VFTETTRNVL ELMITRMTYL RVLSGTTAEA GGEVPFPVVQ PEPQALIEPL TNRETEILIA
LSEGLSNREI AERFNITEPT VKTHASNIYG KLGVRRRGQA VVRAKELQLI SR
//
