ID   A0A223CXP3_9BACL        Unreviewed;       753 AA.
AC   A0A223CXP3;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=UvrD-like helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51198};
GN   ORFNames=CIG75_03065 {ECO:0000313|EMBL:ASS74062.1};
OS   Tumebacillus algifaecis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC   Tumebacillus.
OX   NCBI_TaxID=1214604 {ECO:0000313|EMBL:ASS74062.1, ECO:0000313|Proteomes:UP000214688};
RN   [1] {ECO:0000313|EMBL:ASS74062.1, ECO:0000313|Proteomes:UP000214688}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=THMBR28 {ECO:0000313|EMBL:ASS74062.1,
RC   ECO:0000313|Proteomes:UP000214688};
RX   PubMed=25858243; DOI=10.1099/ijs.0.000240;
RA   Wu Y.F., Zhang B., Xing P., Wu Q.L., Liu S.J.;
RT   "Tumebacillus algifaecis sp. nov., isolated from decomposing algal scum.";
RL   Int. J. Syst. Evol. Microbiol. 65:2194-2198(2015).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC         translocating in the 3'-5' direction.; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034617};
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DR   EMBL; CP022657; ASS74062.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A223CXP3; -.
DR   KEGG; tab:CIG75_03065; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000214688; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR048228; HelD_bacillota.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   NCBIfam; NF041464; HelD_BACSU; 1.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 2.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000214688}.
FT   DOMAIN          197..590
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         218..225
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   753 AA;  86796 MW;  63FD7C52BC51A3F2 CRC64;
     MTIKLHRDYG QECTRLDETK DYIEYVLHES EHNEKAIREN IKEAYANLNS LDASEGYIAL
     LTNVKFFEMT RGNIRQLQQV KKRPYFCRID VQPDDTDKIQ PLYIGKASLF RPDTQEPVIV
     DWRSPIANVY YEGRIGEVSY ETATGTERAE LHLKRQYTIE EGNLLDYRDI DITTRDELLQ
     ESLGGSADSR LKDIVSTIQE EQNRVIRADM HRPMIVQGAA GSGKTTIALH RIAYLIYTYG
     DRFNPDQFMI LAPHQLFLKY IADVLPELGV EAVRQTTYLD FVQENIGKKL KLTDPNLRLF
     HFLEGGDDLE QLRFISRFKG SATCKQLIDR YLDRVTLRLL PQDNCMLGKR VIATAEEIAK
     FLREDYVHLP IYKRVEKVKK ILQDRLKVKK KQLQKDILDH YDERLEVALA MQNPVQRKAK
     VIKLMDDKEA LLKKMEADAK TLVKTYMAQF SKLDLAAHYR EFWQDEVLLS TAMSELELRG
     VQEHSLALLG KKRMELEDTA ALLYLQHKLF GLLTEVKVRN LVIDEAQDYS IFQLLALKEV
     LGSEMFTILG DLSQGIHSYR GVESWESVLE TVFPNGNCQF LVLEQSYRTT VEIMTLANRV
     IVHSKTPNLV LAKPVVRHGE EPKQSVFATE QELIAQVLAD SERYRAEGLN SLAVIGKTMA
     ECKRIKHWID HFDTGLSVTV LDEKEDYSGH DLVIVPSYVV KGLEFDGVFI VNLEEEYTTE
     ELDVKLLYVA MTRPLHRLAV YSMEGKTQLL DLI
//