GenomeNet

Database: UniProt
Entry: A0A223D5Q2_9BACL
LinkDB: A0A223D5Q2_9BACL
Original site: A0A223D5Q2_9BACL 
ID   A0A223D5Q2_9BACL        Unreviewed;       287 AA.
AC   A0A223D5Q2;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   08-MAY-2019, entry version 9.
DE   SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:ASS76694.1};
GN   ORFNames=CIG75_18105 {ECO:0000313|EMBL:ASS76694.1};
OS   Tumebacillus algifaecis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Alicyclobacillaceae;
OC   Tumebacillus.
OX   NCBI_TaxID=1214604 {ECO:0000313|EMBL:ASS76694.1};
RN   [1] {ECO:0000313|EMBL:ASS76694.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=THMBR28 {ECO:0000313|EMBL:ASS76694.1};
RX   PubMed=25858243; DOI=10.1099/ijs.0.000240;
RA   Wu Y.F., Zhang B., Xing P., Wu Q.L., Liu S.J.;
RT   "Tumebacillus algifaecis sp. nov., isolated from decomposing algal
RT   scum.";
RL   Int. J. Syst. Evol. Microbiol. 65:2194-2198(2015).
RN   [2] {ECO:0000313|EMBL:ASS76694.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=THMBR28 {ECO:0000313|EMBL:ASS76694.1};
RA   de Groot N.N.;
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP022657; ASS76694.1; -; Genomic_DNA.
DR   KEGG; tab:CIG75_18105; -.
DR   KO; K00074; -.
DR   BioCyc; GCF_002243515:CIG75_RS18105-MONOMER; -.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00067; 3HCDH; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|PIRSR:PIRSR000105-2};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00324627}.
FT   DOMAIN        8    186       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      188    285       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   NP_BIND      12     17       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING      35     35       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING      94     94       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING      99     99       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     121    121       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     145    145       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     277    277       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   SITE        142    142       Important for catalytic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000105-1}.
SQ   SEQUENCE   287 AA;  31217 MW;  A61094B76F691167 CRC64;
     MSMFEQPIGV IGAGTMGIGI AQAAAQAGYE VLLYDLSEEV LLGALGGLRG RLEKRVAAGK
     LPPGESAVLL NRLRPVTRLE LLSETALVVE AAPEKLELKR ELFASLEAVV SPQCILASNT
     SSLPITALAG GLKHPERVVG LHFFNPVPLM QLVEVIQGLR TAARTVYLAR SFAESLGKRT
     VLCQDTPGFL VNRVARPFYG EALRLLQEGV ADVETIDRLA RDGGRFRMGP FQLMDLIGID
     VNLAVSESVF AAMYEEPRYR PHPMQARLVQ AGTLGRKTGR GFYRYDD
//
DBGET integrated database retrieval system