ID A0A223S731_9ACTN Unreviewed; 101 AA.
AC A0A223S731;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase {ECO:0000256|HAMAP-Rule:MF_00434};
DE Short=PHS {ECO:0000256|HAMAP-Rule:MF_00434};
DE EC=4.2.1.96 {ECO:0000256|HAMAP-Rule:MF_00434};
DE AltName: Full=4-alpha-hydroxy-tetrahydropterin dehydratase {ECO:0000256|HAMAP-Rule:MF_00434};
DE AltName: Full=Pterin carbinolamine dehydratase {ECO:0000256|HAMAP-Rule:MF_00434};
DE Short=PCD {ECO:0000256|HAMAP-Rule:MF_00434};
GN ORFNames=CDO52_14975 {ECO:0000313|EMBL:ASU83913.1};
OS Nocardiopsis gilva YIM 90087.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1235441 {ECO:0000313|EMBL:ASU83913.1, ECO:0000313|Proteomes:UP000215005};
RN [1] {ECO:0000313|EMBL:ASU83913.1, ECO:0000313|Proteomes:UP000215005}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90087 {ECO:0000313|EMBL:ASU83913.1,
RC ECO:0000313|Proteomes:UP000215005};
RA Yin M., Tang S.;
RT "The complete genome sequence of Nocardiopsis gilva YIM 90087.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin =
CC (6R)-L-erythro-6,7-dihydrobiopterin + H2O; Xref=Rhea:RHEA:11920,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15642, ChEBI:CHEBI:43120; EC=4.2.1.96;
CC Evidence={ECO:0000256|ARBA:ARBA00001554, ECO:0000256|HAMAP-
CC Rule:MF_00434};
CC -!- SIMILARITY: Belongs to the pterin-4-alpha-carbinolamine dehydratase
CC family. {ECO:0000256|ARBA:ARBA00006472, ECO:0000256|HAMAP-
CC Rule:MF_00434}.
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DR EMBL; CP022753; ASU83913.1; -; Genomic_DNA.
DR RefSeq; WP_017618992.1; NZ_CP022753.1.
DR AlphaFoldDB; A0A223S731; -.
DR KEGG; ngv:CDO52_14975; -.
DR OrthoDB; 15077at2; -.
DR Proteomes; UP000215005; Chromosome.
DR GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
DR CDD; cd00488; PCD_DCoH; 1.
DR Gene3D; 3.30.1360.20; Transcriptional coactivator/pterin dehydratase; 1.
DR HAMAP; MF_00434; Pterin_4_alpha; 1.
DR InterPro; IPR036428; PCD_sf.
DR InterPro; IPR001533; Pterin_deHydtase.
DR PANTHER; PTHR12599; PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE; 1.
DR PANTHER; PTHR12599:SF0; PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE; 1.
DR Pfam; PF01329; Pterin_4a; 1.
DR SUPFAM; SSF55248; PCD-like; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00434};
KW Reference proteome {ECO:0000313|Proteomes:UP000215005}.
SQ SEQUENCE 101 AA; 11684 MW; 88361FB626221639 CRC64;
MTLLNEQQIT DGLTHLDDWE WDREHHEIRR TVKMPDFMSA IHLITAIAHV AEQANHHPDM
DIRYNKVTFH QTTHAAHGIT ENDMQLAARI DELVADAQPR G
//
