ID A0A223SE47_9ACTN Unreviewed; 527 AA.
AC A0A223SE47;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Mycofactocin system GMC family oxidoreductase MftG {ECO:0000313|EMBL:ASU86395.1};
GN Name=mftG {ECO:0000313|EMBL:ASU86395.1};
GN ORFNames=CDO52_23065 {ECO:0000313|EMBL:ASU86395.1};
OS Nocardiopsis gilva YIM 90087.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1235441 {ECO:0000313|EMBL:ASU86395.1, ECO:0000313|Proteomes:UP000215005};
RN [1] {ECO:0000313|EMBL:ASU86395.1, ECO:0000313|Proteomes:UP000215005}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90087 {ECO:0000313|EMBL:ASU86395.1,
RC ECO:0000313|Proteomes:UP000215005};
RA Yin M., Tang S.;
RT "The complete genome sequence of Nocardiopsis gilva YIM 90087.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; CP022753; ASU86395.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A223SE47; -.
DR KEGG; ngv:CDO52_23065; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000215005; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023978; GMC_oxidoreductase_bact.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR NCBIfam; TIGR03970; Rv0697; 1.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000215005}.
FT DOMAIN 13..307
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 386..516
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT BINDING 95
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 103..106
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 232
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 527 AA; 53829 MW; 898FC2D3EFAC4BE0 CRC64;
MPGVRAVLGA DVVIVGAGPT GSALAVRLSD DTTPGAARSV QLLEAGPAPA TCDAVPPEVL
DGTRMAAARP GHALNWSFTG KVAPGTRRPV PRGRVAGGSG AINGGVFIRG TREDFDAIAA
LGHPDWSYER VLPSFAAVEH DHDFAGPPHG RRGPVPVRRT FPGSASPLTE AFWAACRGLG
YPWEPDKNAP GPPGVGPVPV NVVSGIRHSA LLTHLLPHAG RPHLTVRGGV LVRRILFAGT
RAIGVEAETE GRVQVVRGDE IVLAAGAIGS ARLLLLSGVG PADELADLGI RVVHGAPAVG
RAVTDHPGVA VGITPVPSAV PAARTAVVEA ALHAVSTAAD EGTGARRDGD LEIMPYTAPF
TELIPGGAGT PPGEVAFGVT LLRTASSGAI RLASADPHAP PLITYRHLTS AADRARLREG
VRRCAEILTS APLRRLTASY GGPPAAVLGS DRALDTWIGE RVSTANHLSG GCAMGEVTDA
QGRVHGVTGL RVADSSILPR APSRGTAATA AMMGEHLARS FPPTLES
//
