ID A0A223VA64_9FLAO Unreviewed; 536 AA.
AC A0A223VA64;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Peptidase M1 {ECO:0000313|EMBL:ASV31868.1};
GN ORFNames=CJ263_17500 {ECO:0000313|EMBL:ASV31868.1}, GCM10011412_23770
GN {ECO:0000313|EMBL:GGD85209.1};
OS Maribacter cobaltidurans.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Maribacter.
OX NCBI_TaxID=1178778 {ECO:0000313|EMBL:ASV31868.1, ECO:0000313|Proteomes:UP000215244};
RN [1] {ECO:0000313|EMBL:ASV31868.1, ECO:0000313|Proteomes:UP000215244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B1 {ECO:0000313|EMBL:ASV31868.1,
RC ECO:0000313|Proteomes:UP000215244};
RA Wu Y.-H., Cheng H., Xu X.-W.;
RT "The complete genome sequence of Maribacter sp. B1, isolated from deep-sea
RT sediment.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GGD85209.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CGMCC 1.15508 {ECO:0000313|EMBL:GGD85209.1};
RX PubMed=30832757;
RA Wu L., Ma J.;
RT "The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing
RT project: providing services to taxonomists for standard genome sequencing
RT and annotation.";
RL Int. J. Syst. Evol. Microbiol. 69:895-898(2019).
RN [3] {ECO:0000313|EMBL:GGD85209.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CGMCC 1.15508 {ECO:0000313|EMBL:GGD85209.1};
RA Sun Q., Zhou Y.;
RL Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PIRSR:PIRSR634015-3};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR634015-3};
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DR EMBL; CP022957; ASV31868.1; -; Genomic_DNA.
DR EMBL; BMJL01000005; GGD85209.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A223VA64; -.
DR KEGG; marb:CJ263_17500; -.
DR OrthoDB; 100605at2; -.
DR Proteomes; UP000215244; Chromosome.
DR Proteomes; UP000603042; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09603; M1_APN_like; 1.
DR Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR Gene3D; 2.60.40.1730; tricorn interacting facor f3 domain; 1.
DR InterPro; IPR042097; Aminopeptidase_N-like_N_sf.
DR InterPro; IPR014782; Peptidase_M1_dom.
DR InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR PANTHER; PTHR11533:SF303; AMINOPEPTIDASE N; 1.
DR PANTHER; PTHR11533; PROTEASE M1 ZINC METALLOPROTEASE; 1.
DR Pfam; PF01433; Peptidase_M1; 1.
DR SUPFAM; SSF63737; Leukotriene A4 hydrolase N-terminal domain; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PIRSR:PIRSR634015-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000215244};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|PIRSR:PIRSR634015-3}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..536
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012420385"
FT DOMAIN 257..462
FT /note="Peptidase M1 membrane alanine aminopeptidase"
FT /evidence="ECO:0000259|Pfam:PF01433"
FT ACT_SITE 328
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR634015-1"
FT ACT_SITE 402
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR634015-1"
FT BINDING 327
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR634015-3"
FT BINDING 331
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR634015-3"
FT BINDING 350
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR634015-3"
SQ SEQUENCE 536 AA; 62384 MW; DCD203F1C68FFC2C CRC64;
MNKLLLLFAF LLFFQFSNAQ EFTQQDTLRG SITPERAWWD LNYYHLDIEV KPDDKFISGT
NTIRYKVLDA NQVLQVDLQP PLVIEKITQD GENLEFKTNG NAHFVKLEKT QKNGDYNEIV
VHYSGHPKEA VRAPWDGGFS WKEDKNGNDF VATSCQGLGA SVWWPNKDHM YDEVDSMLIS
VKVPKGLMDV SNGRLRKVDK DTNTYHWFVS NPINNYGVNV NIGDYVHFGE TYEGEKGLLD
MDYYVLRDNL EKAKEQFKQA PKMMEAFEHW FGPYPFYEDS FKLVEVPYLG MEHQSSVTYG
NQYGNGYLGR DLSGTGWGLK FDYIIIHEAG HEWFANNITY KDIADMWVHE GFTMYSESLF
IEYYYGKEAA SEYLLGIRKN IRNDRPLIGP YAVNKAGSGD MYNKGANMLH TLRQVMNDDE
KWRATLRGLN KEFYHETITS DQIEHYLSVQ MGGDFRPFFN QYLRTTDIPV FEYQIDGGLL
KYRYQKVVEG FNMPLRIFLD KEPKWITPSS NWQQLSIKKG TSIEVDPNFY VDVTKI
//
