ID A0A225ACA6_9EURO Unreviewed; 1629 AA.
AC A0A225ACA6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Kinesin-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=UA08_06040 {ECO:0000313|EMBL:OKL58712.1};
OS Talaromyces atroroseus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Trachyspermi.
OX NCBI_TaxID=1441469 {ECO:0000313|EMBL:OKL58712.1, ECO:0000313|Proteomes:UP000214365};
RN [1] {ECO:0000313|EMBL:OKL58712.1, ECO:0000313|Proteomes:UP000214365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 11181 {ECO:0000313|EMBL:OKL58712.1,
RC ECO:0000313|Proteomes:UP000214365};
RA Rasmussen K.B., Rasmussen S., Petersen B., Sicheritz-Ponten T.,
RA Mortensen U.H., Thrane U.;
RT "Talaromyces atroroseus IBT 11181 draft genome.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKL58712.1}.
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DR EMBL; LFMY01000009; OKL58712.1; -; Genomic_DNA.
DR RefSeq; XP_020118833.1; XM_020268729.1.
DR STRING; 1441469.A0A225ACA6; -.
DR GeneID; 31005796; -.
DR OrthoDB; 126886at2759; -.
DR Proteomes; UP000214365; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR CDD; cd01233; PH_KIFIA_KIFIB; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR049780; PH_KIFIA_KIFIB.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF6; KINESIN-LIKE PROTEIN KIF1C ISOFORM X1; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000214365};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 8..361
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1508..1617
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 36..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 612..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 756..821
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 612..629
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 110..117
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1629 AA; 182004 MW; 8E2DF57A2CCB29C7 CRC64;
MAPAGGGNIK VVLTSTASSL ENERNAKCIV QMKGNQTVLT PPPGAEEKMR KGGMKGTPDG
PKTFAFDRSY WSFDKSAPNY AGQENLFADL GVPLLDNAFQ GYNNCIFAYG QTGSGKSYSM
MGYGKEHGVI PKICQDMFKR IATIQEDKNL NCTVEVSYLE IYNERVRDLL NPATKGNLKV
REHPSTGPYV EDLAKLVVRS FQEIENLMDE GNKARTVAAT NMNETSSRSH AVFTLTLTQK
RHDAETTMDT EKVAKISLVD LAGSERATST GATGARLKEG AEINRSLSTL GRVIAALADL
SSGKGKKGTL VPYRDSVLTW LLKDSLGGNS MTAMIAAISP ADINFEETLS TLRYADSAKR
IKNHAVVNED PNARMIRELK EELAQLRSKL GGGAGSIASG GGSGVPMEES YPPDTPLDQQ
MVSIAQPDGT IKKVSKAEIV EQLNQSEKLY KDLNETWEEK LAKTEEIQKE REAALEELGI
SIEKGFVGLS TPKKMPHLVN LSDDPLLTEC LVYNIKPGQT RVGNIDQENA AEIRLNGSKI
RQQHCIFENV DNVVTLIPSE GAAIMVNGLR VEKPTRLRSA CRIILGDFHI FRFNHPEEAR
AERVEQSLLR HSVTTSQLGS PAPSRTHDRT MSKAGSEVEG EMSPTPTPYR GGRDADWFYA
RREAASAILG PDQKISDLND DELNALFDDV QKARAVRRGL LENDEDTDSL SSFPVRDKYM
SNGTIDNFSL DTAITMPGTP RQIDEEEGEF SLQAARDDMQ RQLDRQKGEF QEKLKAEAPH
ADVEEVRQQR TRMEEALRTA KADFEKQLQK QKEQYENHIK EMGHPVPKIY ENGFAKLEPE
EIEVAKTVVR HWSKRNYVRM AESILQHASL LKEAQVMSQI MDKNVVFQFA IIDDGHNMVS
SYDLVLNGIS GEDDSALDEV KKPCVCVRVI DFKHCAIHLW SMEKLQKRVQ AMRQMHQYID
RPDYIQHFKL ENPFSETCPA QYSLVGDADI PLTAVFETRV QDFSVEVVSP YTQSVIGIIR
LSLEPSSAQG PSSTLKFNVV MRDMAGFAER EGTEVHAQLF VPGVSEEGGA TTTQMISGFD
ENPVRFESVH SMSLPLSSLR TVSLKVCIYA KVTPMHLDKL LSWDDMRDSS ETPAPSKRKA
PRIAETEFFS EERHDVFARI QILELAESGD YLPVEVVQNS SMDAGTYQLH QGLQRRVAVH
LTHSSTENFP WEDITNLRVG SVRLLDPWGK IPDQDLQTPD VPLRLIQEPM IKDNADGTSN
VTIIGQWDSS LHGSLLLDRT TAEKYRVQIS LRWDLVSSRV HEPIVFQLDQ TLVILGRTYV
RQQSILRQIW NSTRVVHSTV GMFSVVIRPV SAKRAADLWR MNTQSDYVKG EELLTSWSPR
KVSLVRDFIA SRKRRQRAAE LEAARGALGA DSLVASPLKG SGRSTPMRNQ DFTERQMKLV
QRYLSLWSTR KDPTETILVK TNTEQPTNGD VVSTTNKNNN KALLDASDSH GSAPRYVAAV
QTLSKNATVA KSSYLMMPDD DNSTRWVRRF VELRGSYLHI YSAPEGDEIN TINLRHARVD
HDPDFARLFD NRADGMASSR GRPNIFAVYG PQNTFLFAAR TEAQKVEWIL KIDQSYFSNN
APVNGNGRR
//
