ID A0A225AD50_9EURO Unreviewed; 566 AA.
AC A0A225AD50;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OKL58340.1};
GN ORFNames=UA08_06676 {ECO:0000313|EMBL:OKL58340.1};
OS Talaromyces atroroseus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Trachyspermi.
OX NCBI_TaxID=1441469 {ECO:0000313|EMBL:OKL58340.1, ECO:0000313|Proteomes:UP000214365};
RN [1] {ECO:0000313|EMBL:OKL58340.1, ECO:0000313|Proteomes:UP000214365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 11181 {ECO:0000313|EMBL:OKL58340.1,
RC ECO:0000313|Proteomes:UP000214365};
RA Rasmussen K.B., Rasmussen S., Petersen B., Sicheritz-Ponten T.,
RA Mortensen U.H., Thrane U.;
RT "Talaromyces atroroseus IBT 11181 draft genome.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|ARBA:ARBA00007812, ECO:0000256|RuleBase:RU362132}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKL58340.1}.
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DR EMBL; LFMY01000010; OKL58340.1; -; Genomic_DNA.
DR RefSeq; XP_020118461.1; XM_020268979.1.
DR AlphaFoldDB; A0A225AD50; -.
DR STRING; 1441469.A0A225AD50; -.
DR GeneID; 31006431; -.
DR OrthoDB; 2291769at2759; -.
DR Proteomes; UP000214365; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004737; F:pyruvate decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd07035; TPP_PYR_POX_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR045229; TPP_enz.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR18968:SF164; PYRUVATE DECARBOXYLASE; 1.
DR PANTHER; PTHR18968; THIAMINE PYROPHOSPHATE ENZYMES; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF00205; TPP_enzyme_M; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000214365};
KW Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132}.
FT DOMAIN 16..104
FT /note="Thiamine pyrophosphate enzyme N-terminal TPP-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02776"
FT DOMAIN 178..282
FT /note="Thiamine pyrophosphate enzyme central"
FT /evidence="ECO:0000259|Pfam:PF00205"
FT DOMAIN 387..542
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 566 AA; 61180 MW; 50741B7F3D0C16FA CRC64;
MEAMVKGQKE RKGQWPKAIT CPNEMVALSM ADGYARLTGK PQCVIVHVDV GTQGLGAAVH
NASCGRAPVL IFAGLSPFTL EGEMRGSRTE YIHWIQDVPD QKQIISQYCR YTGEFKSGKN
VKQIVNRALQ WATSDPQGPV YLAGAREIME EEIEPYSLNQ KQWVPVTGSA LPASAVELIA
NELVNAKEPL VVVGYNGRAA SSVKELVNLA NLVKGLRVLD CAGSDMSFPA DHPGWLGLRF
GNSDAVKTAD VILVVDSDVP WIPTVCKPKE TAKVIHLDVD PLKQQIPMFY LPSIATFKVD
STTAFKQINE YIVSNPTLSQ TLNSEEVNNR QRRVEESYRQ RLQEIADSAV APTGGPDAHL
NANYLMAELR KAAPQDTIWA IEAVTLTLFV ADQLQCTLPK SWINCGGGGL GWSGGGALGI
KLASDDEHGG KNKGKFVCQI VGDGTYLFSV PGSVYWIARR YNIPILTIVL NNKGWNAPRR
SMLLVHPDGE GSKATNEELN ISFSPTPDYA GIAKAAAGGE LWAGRASTVG ELAEKLPQAI
QSVLAGTAAV LEAQLDGIVG KYVEKK
//
