ID A0A225AHD6_9EURO Unreviewed; 961 AA.
AC A0A225AHD6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN ORFNames=UA08_03931 {ECO:0000313|EMBL:OKL60842.1};
OS Talaromyces atroroseus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Trachyspermi.
OX NCBI_TaxID=1441469 {ECO:0000313|EMBL:OKL60842.1, ECO:0000313|Proteomes:UP000214365};
RN [1] {ECO:0000313|EMBL:OKL60842.1, ECO:0000313|Proteomes:UP000214365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 11181 {ECO:0000313|EMBL:OKL60842.1,
RC ECO:0000313|Proteomes:UP000214365};
RA Rasmussen K.B., Rasmussen S., Petersen B., Sicheritz-Ponten T.,
RA Mortensen U.H., Thrane U.;
RT "Talaromyces atroroseus IBT 11181 draft genome.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKL60842.1}.
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DR EMBL; LFMY01000004; OKL60842.1; -; Genomic_DNA.
DR RefSeq; XP_020120963.1; XM_020266285.1.
DR AlphaFoldDB; A0A225AHD6; -.
DR STRING; 1441469.A0A225AHD6; -.
DR GeneID; 31003686; -.
DR OrthoDB; 5476186at2759; -.
DR Proteomes; UP000214365; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47968; CENTROMERE PROTEIN E; 1.
DR PANTHER; PTHR47968:SF36; CENTROMERE-ASSOCIATED PROTEIN E; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394}; Coiled coil {ECO:0000256|SAM:Coils};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Reference proteome {ECO:0000313|Proteomes:UP000214365}.
FT DOMAIN 210..567
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 1..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 831..896
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 910..961
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 591..630
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 33..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 852..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 291..298
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 961 AA; 104377 MW; 86630F5B29E1F816 CRC64;
MSLPPKKLKP LSAISDAQRA ASPSPSKLRP PSRPSLGGNN QLGSAMRSIS GTITPIGTDK
TVRRSVSIAS FPQPPKSSGR LSMASVSSSA SHATTTTPRG TPDITKSGTM KARKQSRLSS
GTTMSNRSSK TVSLLDHSSD GKTVLNAAVG RDSEGQFSIS SPPHSRSSSA QGSYSTSATT
FDENEETEHG AMDPKDTSKK SPRSKEVKGN VIVSVRVRPD NGAHDNSRTE GEWMVDGRRS
LISFRGKESG DYLYDNVFTT HDNNSRVYDS SAKRLVRRVM EGYHGTVFAY GMTGTGKTFS
MQGTASSPGV IPLAITDIFS YIRETPHREF LLRVSYLEIY NEKIHDLLSA STANGPGAPA
QQEEIKLRED SKRGVYATPL KEEIVQSPTQ LLRVIARGDH ARRTGSTQFN ARSSRSHAVV
QIVVESRERA PSGNAIQDKR SAVAPGGVRV STLSLIDLAG SERAAENKER RTEGAHINKS
LLTLGTVIAR LSESKEKATN SADKEGKHLP YRDSKLTRLL QPALSGNSLV SILCTIQIGA
SGSAAPANSH TNETLNTLKF AARAKNNIVS HAKKAEEAYG GNGDGGSRVL LERYRMEIQS
LRAQLESQSK TQAENDLKME EERMEKEAEA RHEEQMLEMQ LARTALKERI EHLNRLILSS
KSTGVNSQSA AAAFDRSSSM SGVNDTRTRS LYSTSSQSTL GANSLRRAVS QQSLHGGDHL
NNFQNQRSSV VHDEDDDTVG EFGDGTASLQ MQVTALQADL ADKNRYISTL ERRLLQARRS
SHSRMSMGLS QLKNGDDADM MALLREKDME ISELRIQMDD KDRMLTALRS AARQRDVAQM
TADVPGQEKR MGHHNSGSNA SSLASGPPLS SGSPVNTVSL ASISEREVNP NRRSVDEVSR
MLDEMIQDRV EHGHFTKTSR RSVLSSNGPS SYTEPIATKA TASSVSESRT SIVEMPADVQ
Y
//
