ID   A0A225DGG1_9BACT        Unreviewed;       945 AA.
AC   A0A225DGG1;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=TolB protein periplasmic protein {ECO:0000313|EMBL:OWK40552.1};
GN   ORFNames=FRUB_05471 {ECO:0000313|EMBL:OWK40552.1};
OS   Fimbriiglobus ruber.
OC   Bacteria; Planctomycetota; Planctomycetia; Gemmatales; Gemmataceae;
OC   Fimbriiglobus.
OX   NCBI_TaxID=1908690 {ECO:0000313|EMBL:OWK40552.1, ECO:0000313|Proteomes:UP000214646};
RN   [1] {ECO:0000313|Proteomes:UP000214646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SP5 {ECO:0000313|Proteomes:UP000214646};
RA   Ravin N.V., Rakitin A.L., Ivanova A.A., Beletsky A.V., Kulichevskaya I.S.,
RA   Mardanov A.V., Dedysh S.N.;
RT   "Genome analysis of Fimbriiglobus ruber SP5, the first member of the order
RT   Planctomycetales with confirmed chitinolytic capability.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWK40552.1}.
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DR   EMBL; NIDE01000008; OWK40552.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A225DGG1; -.
DR   OrthoDB; 574237at2; -.
DR   Proteomes; UP000214646; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR024977; Apc4-like_WD40_dom.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19848:SF8; E3 UBIQUITIN-PROTEIN LIGASE TRAF7; 1.
DR   PANTHER; PTHR19848; WD40 REPEAT PROTEIN; 1.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SMART; SM00320; WD40; 2.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   SUPFAM; SSF69322; Tricorn protease domain 2; 1.
DR   PROSITE; PS50104; TIR; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000214646};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        472..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..146
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   REPEAT          729..770
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   945 AA;  106900 MW;  B6DD92FDD6F7143C CRC64;
     MASIFVNYRR EDRHFCDRLN DFLVSSFGKN EIFRDTGSLK EGEDFEKQLE IAISDSKVIL
     VLIGSKWLEE LQRKESSSEK DYAKFEIETA LKFSSKTVIP ILIDEQKMPA SHILPVSIQK
     ICLLHAFTIK SDPSFPGDFA ALANVLKGKC PGLKSPSTED KARGLRSRQF KLHSLHFAIV
     AFLALWTYGT AWLSIGAREK HIMYLAIILG LITLACVSLK VIDVFVCVGF PQLVTRHIHR
     YIVVAIVLIA ILGNRDRIDR NSAIIDKNIM VYMRTWDPLG RYANSHGPQL ADSGRQIDDG
     FFIGYQSPYY VAVNRRYFVL EKDGKTGKTI TKLSDGKGGN EEISLDDSTV RLDDNHWWNG
     KRHLTISNGE RAISVCFTAN EAIDHHNDRT DDMRGESIDR YLKDCREILT KTANSNQFQF
     INTTTHYNFL YDQMVWLYAD VLLFPLPIYV ARFVRRNAAR GILKQRQNIN GYIFFTAIVA
     ATAIATKFQS PLTLFTWEKT STYLSAYDNS INTRGRETLP ADYRGAFFCA GGTRLAVQNN
     DQIKICDINM NSVIRLFYIN NGPGNHFFGG NYVVNWLADD RRFILRRRDG SGLDYIYDTN
     GSVAPFEKSI NRQARPIEIH PDGEHVILED SDGRFYTYDV SASERDGLCD IRRKYTTVKW
     SPDGSKMAID YQHVVSIIDI ASPAFASFIL AKNSSDATML DWSPDGSHLA VLSGNTIKIW
     NIDTRLPVFN HQQTSVTQIA WSPDGAALAT AHSDMKIRIW SIPDGNLLFE SIQYEATIAA
     LCWPMSNART LLICCDTRSG FDVNRLQLYP SLFDGLSSRG RVVFGDDLKS HKEPPGPSVG
     GNHDDQKIID SAKNTILNID HLRDQKQYWH NQLDNALTEP LTPPSAIYSL RYRSWFYSFV
     EQEASAQLAI SKLEIDRSLA HRIAASVMRA KRPPGPKLPK ATETE
//