ID A0A225DGM2_9BACT Unreviewed; 1461 AA.
AC A0A225DGM2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Cobalt-zinc-cadmium resistance protein CzcA / Cation efflux system protein CusA {ECO:0000313|EMBL:OWK37678.1};
GN ORFNames=FRUB_06798 {ECO:0000313|EMBL:OWK37678.1};
OS Fimbriiglobus ruber.
OC Bacteria; Planctomycetota; Planctomycetia; Gemmatales; Gemmataceae;
OC Fimbriiglobus.
OX NCBI_TaxID=1908690 {ECO:0000313|EMBL:OWK37678.1, ECO:0000313|Proteomes:UP000214646};
RN [1] {ECO:0000313|Proteomes:UP000214646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP5 {ECO:0000313|Proteomes:UP000214646};
RA Ravin N.V., Rakitin A.L., Ivanova A.A., Beletsky A.V., Kulichevskaya I.S.,
RA Mardanov A.V., Dedysh S.N.;
RT "Genome analysis of Fimbriiglobus ruber SP5, the first member of the order
RT Planctomycetales with confirmed chitinolytic capability.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK37678.1}.
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DR EMBL; NIDE01000014; OWK37678.1; -; Genomic_DNA.
DR OrthoDB; 219750at2; -.
DR Proteomes; UP000214646; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 4.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF19; CATION EFFLUX SYSTEM PROTEIN CUSA; 1.
DR Pfam; PF00873; ACR_tran; 3.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000214646};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 340..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1247..1264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1271..1291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1307..1331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1366..1385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1397..1418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1461 AA; 160134 MW; 4B380538D1FF8F31 CRC64;
MIERLIEASV RNRFVVLALA AALAVGGVYA TLQTPVDAIP DLSENQVIVF TDWPGRSPRE
IEDQITYPLS LRLQGLAGIK AVRSSSEFNF SMITLIFEES TDFYFARQRV LERLTQAGAF
LPAGVVPYMA PDATALGQVF WYTVEPSPSH PVDPGRLWAV NKFYIAPQLN SAAGVAEVAP
VGGTPLEYQI DVRPETLRTY GVTVGELFSA VSRSNLPAGG GVIQKNNAEY IVRGVGWLKD
TADIENTVVK EINGIPVYVK TVATVQVGTQ FRRSVFEKDG NEVVGGVVLM RHGGNPLAVT
ERVKAKIQEL QPGLPPGVQI VPAYDRTRLI TGAIHTLTEV MWHEMLIAGV AILLILGHVR
SVFVICVTLP LSVLFSFLLM FLLRKLGVID IQANVMSLAG ITISIGILVD QAIVMTENAT
HHLKERFGDQ KVTGDTREIV VRACRTVGRP IFFSVLIMLL SFVPVFMLSG REGKYFHPLA
FTKSFALLGV ALISVTVVPA LIPTFIRGRL RSEEENWIVR GFIRVYRPLL TWALPRRNLV
MWAFAALLIL AAGLFPVQAL VGMGASESAW GAMFLIVFGV VTVLTVAFTR GFLPQAVSLA
TLVLLALWAW HFPKIGVSFM PALDEGTTLD MPVTVPRVSV TEAADDLKAR DALLRGFPEV
ESVVGKAGRA DTPTDPAPLD MVETFVNFRP RELWPKRVLR FPDADLQTRA VLRALEDRGY
LLPAPHADDR ENVVNEAAQR ALERFDETIR ELALRHYVEF EQELGPMLTR FVVAETLRRM
REAGHLDALT AGDEAKLAEE LSTQLTPDEG VRLAKQPALE AITRIQRQTT ETLAARKVIG
DAAVALEIHE GRLGQALGTL RESLGGVRET LAGAVLRATN DRRHGAWIES VNKVNWELFD
RGTEAFTWYA IDELVASGSR VALVQAAPLG IEAERFAAAS KNVRLGKPYD ADALEPLGKL
RAELEGPFRE RVFLWRRTGG PKGDLVDDEF GRVLQVPGWS NIFTQPIINR IEMLSTGVRT
DIGIKVFGPD LDTVDRVCKR IEAAVKPVPG ARDVIAAPIM GKGYLDVTID RERAARYGVT
VEDIETEIEM ALGGRVVTQT VEKRDRFPVR VRYARAGRED EEAVKRLLVT GSARADRPAG
DAMSANTTTV AAHPAAPGPA HAARGKVLIP LASVADVRIV EGPAVIKSEN GRLLNYVTLN
VRGRDAVGFV EEARRVVEQK VKLPEGVHVE WAGEFEHQER AARTLKIVLP VVILVIFLLL
YLTYHDFADA VLMMLAVPEA LAGGAFFLYF FPKLVYGWHS PPVDFSVAVW VGFIACFGMA
TETGIIMLVY LREAIEKRGG LENIRSLDEL REAVIEGAVH RLRPKLLTEG VAIVAIFPMV
FASGVGGEVL APMALPVLGG LLISDEVVDL FLPVRFYWVR RARWLKLQEE KARSAAAAEQ
VALVRAMDGS DVVAGTAGGV V
//
