ID A0A225DQ37_9BACT Unreviewed; 437 AA.
AC A0A225DQ37;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=3-isopropylmalate dehydratase large subunit {ECO:0000313|EMBL:OWK38505.1};
GN ORFNames=FRUB_07625 {ECO:0000313|EMBL:OWK38505.1};
OS Fimbriiglobus ruber.
OC Bacteria; Planctomycetota; Planctomycetia; Gemmatales; Gemmataceae;
OC Fimbriiglobus.
OX NCBI_TaxID=1908690 {ECO:0000313|EMBL:OWK38505.1, ECO:0000313|Proteomes:UP000214646};
RN [1] {ECO:0000313|Proteomes:UP000214646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP5 {ECO:0000313|Proteomes:UP000214646};
RA Ravin N.V., Rakitin A.L., Ivanova A.A., Beletsky A.V., Kulichevskaya I.S.,
RA Mardanov A.V., Dedysh S.N.;
RT "Genome analysis of Fimbriiglobus ruber SP5, the first member of the order
RT Planctomycetales with confirmed chitinolytic capability.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK38505.1}.
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DR EMBL; NIDE01000014; OWK38505.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225DQ37; -.
DR OrthoDB; 9802769at2; -.
DR Proteomes; UP000214646; Unassembled WGS sequence.
DR GO; GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:InterPro.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:InterPro.
DR CDD; cd01583; IPMI; 1.
DR Gene3D; 3.30.499.10; Aconitase, domain 3; 2.
DR InterPro; IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
DR InterPro; IPR001030; Acoase/IPM_deHydtase_lsu_aba.
DR InterPro; IPR018136; Aconitase_4Fe-4S_BS.
DR InterPro; IPR036008; Aconitase_4Fe-4S_dom.
DR InterPro; IPR006251; Homoacnase/IPMdehydase_lsu.
DR InterPro; IPR033941; IPMI_cat.
DR NCBIfam; TIGR01343; hacA_fam; 1.
DR PANTHER; PTHR43822:SF2; 3-ISOPROPYLMALATE DEHYDRATASE LARGE SUBUNIT, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43822; HOMOACONITASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00330; Aconitase; 2.
DR PRINTS; PR00415; ACONITASE.
DR SUPFAM; SSF53732; Aconitase iron-sulfur domain; 1.
DR PROSITE; PS01244; ACONITASE_2; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000214646}.
FT DOMAIN 23..296
FT /note="Aconitase/3-isopropylmalate dehydratase large
FT subunit alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF00330"
FT DOMAIN 296..427
FT /note="Aconitase/3-isopropylmalate dehydratase large
FT subunit alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF00330"
SQ SEQUENCE 437 AA; 47019 MW; 550049A78328EACE CRC64;
MSAMTLTEKV LARAADRTAV DPGNNIWVNV DILMTHDVCG PGTIGVFKKH FGKDAKVWDR
EKVVIIPDHY IFTKDAMANR NVDVLRQFVA EQDIKYYYDV GTPNYKGVCH IALPEEGHTR
PGEVLLGTDS HTCTAGAFGQ FATGIGNTDA GFVMGTGKTW LKVPPTMRFV FHGQMPPYLM
AKDLILAVIG DIGVDGATYR AMEFDGDGIY ALNIEERMTL CNMAIEAGGK NGCIAPDQIT
LDYVNARGVK TGNKPFTVFK SDPGAKFIYE KVYDVSKLEP VIAKPHSPDN KALVSEVQGT
RLDRAYIGSC TGGKLTDFRA AAGILKGKEV KIDTFVVPAT TEVARGLDTE KIGGKSLRDI
FLAAGAKIGD ASCAACLGGP SDTFGRLNTP ISCISTTNRN FPGRMGHKQA QVFLASPLTV
AASALTGHIQ DPRMFVA
//
