ID   A0A225MU03_9BURK        Unreviewed;       484 AA.
AC   A0A225MU03;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=2-hydroxymuconic semialdehyde dehydrogenase {ECO:0000313|EMBL:OWT62129.1};
GN   ORFNames=CEY11_08120 {ECO:0000313|EMBL:OWT62129.1};
OS   Candidimonas nitroreducens.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Candidimonas.
OX   NCBI_TaxID=683354 {ECO:0000313|EMBL:OWT62129.1, ECO:0000313|Proteomes:UP000214603};
RN   [1] {ECO:0000313|Proteomes:UP000214603}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC-089 {ECO:0000313|Proteomes:UP000214603};
RA   Fan M., Lin Y.;
RT   "Herbaspirillum phytohormonus sp. nov., isolated from the root nodule of
RT   Robinia pseudoacacia in lead-zinc mine.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWT62129.1}.
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DR   EMBL; NJIH01000004; OWT62129.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A225MU03; -.
DR   OrthoDB; 6187633at2; -.
DR   Proteomes; UP000214603; Unassembled WGS sequence.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd07093; ALDH_F8_HMSADH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR017628; OHmuconic_semiald_DH.
DR   NCBIfam; TIGR03216; OH_muco_semi_DH; 1.
DR   PANTHER; PTHR43720; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43720:SF2; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345};
KW   Reference proteome {ECO:0000313|Proteomes:UP000214603}.
FT   DOMAIN          12..480
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        252
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   484 AA;  52421 MW;  5FFC3E890DFDD496 CRC64;
     MTEFKNFIDG QWVATDRTFE NRNPADNSLI GPVHEAGRPE VDAAVAAARA ALRGPWGKLK
     TQQRVDLLHA LVDGINRRFD DFLDAEMRDT GKPYGLASHL DIPRGAANFR VFADLIRNVP
     NESFGMDTPD GGRALNYAVR APRGVIGVIC PWNLPLLLMT WKVGPALACG NTVVVKPSED
     TPATATLLGE IMNEVGVPPG VYNVVHGYGP DSAGEYLSTH PGVDGITFTG ETGTGEAIMA
     AAAKGLRPVS LELGGKNPGI VFADADFDKA VAGIARSTFE NTGQVCLGTE RVYVQRPIFE
     RFVAALKVRA EAYRLGDPFD RAVDFGPLVS LKHREKVLSY YQRARDEGAT VVTGGGIPDM
     PGALRDGAWI QPTIWTGLPE SSAIVREEIF GPCCHVQPFD TEQEAIDMAN DTRYGLAATA
     WTRDLGVAHR LGEALDVGLC WINSWFLRDL RTSFGGARQS GIGREGGVHS LEFYTELRNV
     CVRL
//