ID   A0A225NNU4_9RHOB        Unreviewed;       317 AA.
AC   A0A225NNU4;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Glycerate dehydrogenase {ECO:0000313|EMBL:OWU75610.1};
DE            EC=1.1.1.29 {ECO:0000313|EMBL:OWU75610.1};
GN   ORFNames=ATO3_05135 {ECO:0000313|EMBL:OWU75610.1};
OS   Marinibacterium profundimaris.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Marinibacterium.
OX   NCBI_TaxID=1679460 {ECO:0000313|EMBL:OWU75610.1, ECO:0000313|Proteomes:UP000215377};
RN   [1] {ECO:0000313|EMBL:OWU75610.1, ECO:0000313|Proteomes:UP000215377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=22II1-22F33 {ECO:0000313|EMBL:OWU75610.1,
RC   ECO:0000313|Proteomes:UP000215377};
RA   Lai Q., Li G., Shao Z.;
RT   "Oceanicola sp. 22II1-22F33 Genome Sequencing.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWU75610.1}.
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DR   EMBL; AQQR01000002; OWU75610.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A225NNU4; -.
DR   OrthoDB; 9793626at2; -.
DR   Proteomes; UP000215377; Unassembled WGS sequence.
DR   GO; GO:0008465; F:glycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   CDD; cd12162; 2-Hacid_dh_4; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003719,
KW   ECO:0000313|EMBL:OWU75610.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215377}.
FT   DOMAIN          20..315
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT                   catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00389"
FT   DOMAIN          106..286
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   317 AA;  35179 MW;  D39CD9B8B097953E CRC64;
     MRIVFLDRGS IGPSVELHRP SFEHDWVVYD QTAPDQVAER LADADIAISN KVPIRRDSIE
     KCPKLKMIAI PATGYDAFDL EACRERGIVV SNVRGYAINT VPEHTFALIL ALRRSIVGYR
     QDVIDGEWQK SGQFCFFNHP IKDLRGSKLG IIGEGVLGQG VADLARAFGM EIMFAAHKGV
     DGLGPLYTPW DQVIETADII TLHSPLMPAT KNMIAEPEFR RMKQKPLLVN CSRGGLVHEG
     DLVKALDEGW ISGVGFDVLT SEPPAPDNPL LKVLDRPNVI VTPHVAWASE EAMQTLWNQV
     RDHLENFERG EPSNVVT
//