ID   A0A225UT28_9STRA        Unreviewed;       452 AA.
AC   A0A225UT28;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=RNase H type-1 domain-containing protein {ECO:0000259|PROSITE:PS50879};
DE   Flags: Fragment;
GN   ORFNames=PHMEG_00033578 {ECO:0000313|EMBL:OWY96210.1};
OS   Phytophthora megakarya.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4795 {ECO:0000313|EMBL:OWY96210.1, ECO:0000313|Proteomes:UP000198211};
RN   [1] {ECO:0000313|Proteomes:UP000198211}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA   Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA   Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT   "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT   of cacao black pod achieved similar genome size and gene model numbers by
RT   different mechanisms.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWY96210.1}.
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DR   EMBL; NBNE01011945; OWY96210.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A225UT28; -.
DR   EnsemblProtists; OWY96210; OWY96210; PHMEG_00033578.
DR   OrthoDB; 49911at2759; -.
DR   Proteomes; UP000198211; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR33064; POL PROTEIN; 1.
DR   PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198211}.
FT   DOMAIN          194..326
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
FT   REGION          356..382
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         452
FT                   /evidence="ECO:0000313|EMBL:OWY96210.1"
SQ   SEQUENCE   452 AA;  51114 MW;  C3BB726D411828A9 CRC64;
     MKGSFNQYHI AEKEVLAILL VLKQFRPLIY GSETPIISKP FVIIPHANPW AACADLGQGH
     EGIIQPVCFT GRVLNGSELR YHIAEKEVLA ILRVLKQFRP LIYDTNHIYT RYSVLKWLLK
     SNSADGRHLK WGLELSKWTL ELRCVQRDED GLAAILGAGI TPREHLDEVA EDLIPAKGRI
     KAPPSISVEM LDSDFEGYVL SFDGAAKVST RQGSCGCILW RLPSWYHLSA HGFPLDDVTV
     NDAEYHGLIK GLELAVDRGF RDVVVVGDSR IVIQQAQGLI GCHQPNLQRR LAEYEALKVK
     FGSVRLGHVK RYYNQAADYL TTKTLALGKA WVVEDADELM HLKFVSRILE KIMKTPETSE
     RKDDASQSLK SDSPSDLVLD SAPSAPETVI PVKIVTTRSR SRQVAQVDDP SRSLDYRDER
     WRRIKAHQNE DPELKRLKDY LKGDLLNYTR KE
//