ID A0A225V1K3_9STRA Unreviewed; 1007 AA.
AC A0A225V1K3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ABCA1 lipid exporter {ECO:0000313|EMBL:OWY99715.1};
DE Flags: Fragment;
GN ORFNames=PHMEG_00029244 {ECO:0000313|EMBL:OWY99715.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWY99715.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWY99715.1}.
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DR EMBL; NBNE01008232; OWY99715.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225V1K3; -.
DR STRING; 4795.A0A225V1K3; -.
DR EnsemblProtists; OWY99715; OWY99715; PHMEG_00029244.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 311..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 948..967
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 580..810
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OWY99715.1"
SQ SEQUENCE 1007 AA; 110765 MW; 14DEBE42C4AE7B0B CRC64;
DGLRLEELST SDLAACRTGV MAEGLVNTDT SSPYTVPTEC DGKVVPYKIG IAPDNAFTRN
YFAETMDMWY PRVDLLDSTT ATVTIPSFKD SIQFFDTNDA LTEYVKSDTY GDNFANPKIY
AAIVFDSAPS GDDIGTFASI EYSLRLNSTQ GDDIDSVGRV PTTDGSLSDV DLFQKDIVTD
YYSVYTVTGF MTLQTLVTRF VTCMPEWNLA NQSTTGVCQR PQTTALASSE RDNTLLNVLA
EDSLIQEALG ALGLSNTVNF SSALNSLPNS TRETLLTPLR QAPQSMLGST VAPFPVDDYT
SSPFYDNVST VFSIVFIMAY LFTISRILVV LIQEKELRQR EFMKILGVTE KTIFLTWYMT
YAAILFVGAV IQALAGLAGL FPNSSLIVTF LFFFLFGMSV LALAFLISTL FSKARVGAFV
GMVAFFAMYA ISQGFSTGTA ENTKRVGSIL SPVALSLGVN VLANAEKTGE GVQFSTMDTL
SDNYRISTAV LMFAFDTVLY TVLGLYFSKV MPKEYGTSLK WYFPVSPSYW RSRKQRQLTN
QTPTDALLDN DSVLDLNPDF EPISTDLRDQ EQRGEALTVK RLRKVFPVPG GEKIAVKGLD
ITMYKDQITC LLGHNGAGKT TLISMLTGMT APSNGNATYR GMSINEDMDE MRQSLGICFQ
HDVLFPELTV QEHLQFFGQI KGYANEELQA VVDKQIREVG LTEKRNSKPN DLSGGMKRKL
SVAVSLLGDS SLVFLDEPTS GMDPYSRRST WEILLNNRND RVMVLTTHFM DEADILGDRI
AIMAEGEMRC CGSSLFLKNR FGAGYNLTLV KDDARCDDDA VASFVTSYVP AAQLLSNVGS
EIAFQLPLHS SSSFAEMFAE MDRQLQSLGL LSYGVSVTTL EEVFIKVAEL ADENDQHTLG
KAARMNSAGS DGFYQSCDEI ITTESIFMRH LRALLLKRFR YAKRDKKTII YVAALPILLI
AAGLGILKSS MAINDDPLKP LTTDEYTGSQ TPTPYFCQAG AGVGECV
//
