ID A0A225V2K5_9STRA Unreviewed; 352 AA.
AC A0A225V2K5;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=N-acetylgalactosaminide beta-1,3-galactosyltransferase {ECO:0000256|ARBA:ARBA00012557};
DE EC=2.4.1.122 {ECO:0000256|ARBA:ARBA00012557};
GN ORFNames=PHMEG_00030560 {ECO:0000313|EMBL:OWY98629.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWY98629.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-
CC galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-
CC galactosaminyl derivative + H(+) + UDP; Xref=Rhea:RHEA:15621,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:28257, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:66914, ChEBI:CHEBI:133470; EC=2.4.1.122;
CC Evidence={ECO:0000256|ARBA:ARBA00000862};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T
CC subfamily. {ECO:0000256|ARBA:ARBA00006462}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWY98629.1}.
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DR EMBL; NBNE01009223; OWY98629.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225V2K5; -.
DR STRING; 4795.A0A225V2K5; -.
DR EnsemblProtists; OWY98629; OWY98629; PHMEG_00030560.
DR OrthoDB; 74967at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030248; F:cellulose binding; IEA:InterPro.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR026050; C1GALT1/C1GALT1_chp1.
DR InterPro; IPR035971; CBD_sf.
DR InterPro; IPR000254; Cellulose-bd_dom_fun.
DR InterPro; IPR003378; Fringe-like_glycosylTrfase.
DR PANTHER; PTHR23033; BETA1,3-GALACTOSYLTRANSFERASE; 1.
DR PANTHER; PTHR23033:SF14; GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED; 1.
DR Pfam; PF00734; CBM_1; 1.
DR Pfam; PF02434; Fringe; 1.
DR SMART; SM00236; fCBD; 2.
DR SUPFAM; SSF57180; Cellulose-binding domain; 1.
DR PROSITE; PS51164; CBM1_2; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000313|EMBL:OWY98629.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000313|EMBL:OWY98629.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..352
FT /note="N-acetylgalactosaminide beta-1,3-
FT galactosyltransferase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013053352"
FT DOMAIN 75..109
FT /note="CBM1"
FT /evidence="ECO:0000259|PROSITE:PS51164"
SQ SEQUENCE 352 AA; 41251 MW; BF0D827DDCA24AAB CRC64;
MKFAATIIAM TIALSNVEAN TPTHLRVLTD EAAMDYSSAP VAEWGQCKWV DRSATCADGL
QCVVYSDWYG QCVKKVASTW GQCGGKGWTG SCTSGNICQK MNDYYSHNMS DTIVVAANTS
TERRYEVVQL DIVADHEHLW LRTRAALQYL HEHFRHDYDW FYKCDDDTYA IIENMRAYLK
RPEIVQRYNR EPMQMGHRFN MPKRDLDYYI TNENLLSKWH QRWDRMVYNS GGAGYVMNRL
YLDKFVESLP EWTCLPDEAS GVMPEDSGVS FCMMWNDVYP WDTRDHRGRE RWHAFNPKLI
FREWNNENYW YVQYHNTVGG RSLYFCRSEH DDIATFNKKF GLAIGDKVMA TN
//
