ID A0A225V4L8_9STRA Unreviewed; 531 AA.
AC A0A225V4L8;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:OWY99877.1};
GN ORFNames=PHMEG_00029046 {ECO:0000313|EMBL:OWY99877.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWY99877.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWY99877.1}.
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DR EMBL; NBNE01008090; OWY99877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225V4L8; -.
DR EnsemblProtists; OWY99877; OWY99877; PHMEG_00029046.
DR OrthoDB; 858418at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR34072; ENZYMATIC POLYPROTEIN-RELATED; 1.
DR PANTHER; PTHR34072:SF48; RIBONUCLEASE H; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:OWY99877.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:OWY99877.1};
KW Transferase {ECO:0000313|EMBL:OWY99877.1}.
FT DOMAIN 4..92
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|Pfam:PF00078"
FT DOMAIN 169..274
FT /note="Reverse transcriptase RNase H-like"
FT /evidence="ECO:0000259|Pfam:PF17917"
SQ SEQUENCE 531 AA; 61451 MW; 4BCEBF7D7ED426D5 CRC64;
MLWEWLVMPQ GLNNASATFN RCVMHLLRSV RDFAPSYFDD VYVHSRAVNE KTDVEMNKER
LQELLGLMRK HKLYANLKKC IFGASEIPVL GCLVGKNGVR PDPEKVRVIK EWPTPSNVKE
LRQFLGLATY LCKYLLKKEA AWTWTAKCQQ AFDAVKLGLT EAPILAVADQ DRPFHVVRDA
SDFAIGCALM QLDHEGRDRA VYYQSRQLKP AERNYPVHDK KILAMKYALA KFRVYLLSNT
PFVVYTDHAS LRTAVKSPHI SQRMARWLSF FAEYNVRVEY KPGRLNVVAD ALSRRPDYDV
KIADVNRIDV ARTYTPSSPL LDEVKAAYAH DADAKQLIEF HSAPSNKPRR KLAPRLRASA
HRYRVHDGLL LYSAVNDNAE RIVVPNEPDL RSRIMYEYHN TYSLLTRDFY WNHQYQWVRK
YVRTYDVYQR VKPASHSQAL LQPLPTPSEC WESVSMDFVF DLPRDSRRKT GIVFFVDRFS
KMVHLAAVAA EVTSVQTARL FVDMLSSLST NDKQSFDLYK MQLQLLRIGR S
//
