ID A0A225VRU8_9STRA Unreviewed; 707 AA.
AC A0A225VRU8;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=RNase H type-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHMEG_00019844 {ECO:0000313|EMBL:OWZ07729.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ07729.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ07729.1}.
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DR EMBL; NBNE01003424; OWZ07729.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225VRU8; -.
DR EnsemblProtists; OWZ07729; OWZ07729; PHMEG_00019844.
DR OrthoDB; 87389at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198211}.
FT DOMAIN 4..94
FT /note="Reverse transcriptase RNase H-like"
FT /evidence="ECO:0000259|Pfam:PF17917"
FT DOMAIN 176..286
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
FT DOMAIN 508..566
FT /note="Integrase zinc-binding"
FT /evidence="ECO:0000259|Pfam:PF17921"
FT REGION 373..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 80375 MW; F0D243858F1664E8 CRC64;
MLYANEWALS AILMQMHDDK LHPLRFCAGV LQDPEMNYHS AEKEVLALLL LLKVCYTHLA
GKTLHVYTRF SAPGWVHKSK SLFGRAVQFA VLLSPWQLEM QRVREKDCVF PLLLQSTITN
FVDLDDSLAL VAPPTKGSPS TRLDPSLLYA QLPHDYEGFV VSFDGSAQTE KNGVYGSCSW
IVWKLPEWQI VIAASAYLEQ TTVNMAEYRG MNHGVIAALG RGAEDLVIVG DSRLAIQQSL
GVLACRMDSL MTLLNRHREL VAKLKSVRYL HVVREYNAAA DSLAGEALES KVSKVVLNDH
SKTELKELNR IQEMIYEPSS DDIKVENASS ESFAQILEGN TCYIHAMDSD ILLQRKISVD
FGHQERAEVS AITRSQTKTK KKRVHFEDEV PERTTNTEAT EAVNENSETQ GQRPSAEFRY
ERTADEIDPV TVQEEQSRRI AKAQDEELRW SNLKAVLRGE TTAMTYNEAR EAWKWADNFV
LSSDNVLYYT SVSRRKVDEP EMSLRLVVPS TMIQEVLHNC HDSIEGGHQG VVRSYQRVKY
DYYWIGLYAD VEKHVKSCLD CSSSKSLPQL RGYSPGNVLA ERPFQVVSMD FVIPLPRSRR
GNTALLLWQC SFTGFVIAKA MSDTDALTVA KVFEEYIYRR FDWDEIAERL VFAINNSHDM
TRKETPFYLV HGWDAHTTLR AMTTSMKRGV GKQTEALACR REINRQQ
//
