ID A0A225VXP5_9STRA Unreviewed; 376 AA.
AC A0A225VXP5;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:OWZ09340.1};
GN ORFNames=PHMEG_00017975 {ECO:0000313|EMBL:OWZ09340.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ09340.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ09340.1}.
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DR EMBL; NBNE01002827; OWZ09340.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225VXP5; -.
DR EnsemblProtists; OWZ09340; OWZ09340; PHMEG_00017975.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF13456; RVT_3; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:OWZ09340.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:OWZ09340.1};
KW Transferase {ECO:0000313|EMBL:OWZ09340.1}.
FT DOMAIN 40..125
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
FT DOMAIN 283..332
FT /note="Integrase zinc-binding"
FT /evidence="ECO:0000259|Pfam:PF17921"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 376 AA; 42379 MW; 710FA28F69FA66B1 CRC64;
MLSSDHIEHL PKEMGQGRRL HSLEPPELGD CGDHGTLSLE GTVNEAEYSG LVKGMQRAIN
AMAQELVLEL PVNNTAAPGG YRLYPTHPLR LLQEAEGLQA KFKSLRLAHV KRDFNAAADY
ISKRAIQEQS SLEVTDLGER KLLQGLNRIH EKPMKDPSPR EQSLVECAFI ATARGIPRVG
EPGTEGAEEG LEVGPRNPDS QDSKEDFEDA RRERWRRICS HQTHDPGLAP LVRFLRGETE
QMSLRQTTHL AKMTDLFVMD FRDALFNVSR NNQNTRGTLS IYILHHCHAD LQGAHQGITR
TYERLRKEFY WIGMFKDTER YVKECVDCVT AKGLLRNPGS SPGNLLATRP FQVVPMDFII
PLPQSARGNR ALLLFQ
//
