ID A0A225VYB2_9STRA Unreviewed; 956 AA.
AC A0A225VYB2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:OWZ10345.1};
GN ORFNames=PHMEG_00016820 {ECO:0000313|EMBL:OWZ10345.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ10345.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ10345.1}.
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DR EMBL; NBNE01002475; OWZ10345.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225VYB2; -.
DR EnsemblProtists; OWZ10345; OWZ10345; PHMEG_00016820.
DR OrthoDB; 49911at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09279; RNase_HI_like; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR PROSITE; PS50013; CHROMO_2; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:OWZ10345.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:OWZ10345.1};
KW Transferase {ECO:0000313|EMBL:OWZ10345.1}.
FT DOMAIN 584..667
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT DOMAIN 885..937
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 391..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..411
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 956 AA; 108562 MW; 033228244426A9E7 CRC64;
MLCYIGYAIG IFPSLPKNEF GELTISYISH EISAEGFRAM PKIAKSVQEL PFPTTLKRVQ
AKESFEILKR KIVSTPLLRH PDRYKPFVII PHANRWAACA RPRTRILPVR FTGRVLNETV
IRYHEAEKEV IAIMRALDVF ENLVRGCPIK VYTRYSSKRA DGRCVRWEVI LSHWDLEVHK
VQSDEDGLAA IMGAGITPRE HLDEVAESLI PLKGRVKPQP VISVEMLEAD FDGYVLSFDG
AVKTSTRQGS CGCIIWKLPG WKVVTVQGFV LEDVTVNDAE YHGLLKGLTM VAERDIPDVV
VVGDSRIVIQ QVQGLINCNQ PHLQRRLAEY GVLREKFKSV RLVHVKREYN QAADYLTSKT
LAAGESWVVT DPAEMTHLEY SVVVLDSEAP ARETPPCEPT SVQPGPESAP IPTPVRIMTA
VTRSHARGNP SQSDPMGPLE YQADRWRRIK AHQDEDHRLK KFLRGEVDSF SRAQIRRLSK
EADLFVLDSG DVLFRLNHSA QGRPRDQTDM LRLAVPETLR QDILPYAHED VQGGHQGITH
THEKFRTDFY WYGMYADVEA FVKECIVLAE RGAPNQGPSP GNIDPTHPFE IVSMDFVTHL
PESARGNTFL LLFQDMFSGY VMCKPMSSTT AQEVAEAYEE RVFQMVGASS MIRHDQDPRF
MDEVFRQRAT LGYMPQANGQ QERSVQTVIR SKSDWDVHVE RLMFALNTSF DATRLNTPFY
LVHGWDAQGT VLAMLGPKPS GVVERTAAIT AMRKPVQKAY SGKPSEIERS PKPGILSDRT
KAGFSVGDAI WLYIPKAQPG LSHKLAHLWH GPFRIAEVTN NFRVRLKIDD TGYRVNPWVH
ISRLKPRALL PKRPTVRTEI DDDDDLDAAL LPEDSWEVDN TNNEYEVEEI LDLRWSKRTR
TSKRIREYLV KWRGYDEPDW MPLSQLSCGA LLYEFNQGAK ARARFRAIQA GDDHPR
//
