ID A0A225W6S7_9STRA Unreviewed; 531 AA.
AC A0A225W6S7;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:OWZ12869.1};
GN ORFNames=PHMEG_00013905 {ECO:0000313|EMBL:OWZ12869.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ12869.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ12869.1}.
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DR EMBL; NBNE01001732; OWZ12869.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225W6S7; -.
DR EnsemblProtists; OWZ12869; OWZ12869; PHMEG_00013905.
DR OrthoDB; 49911at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:OWZ12869.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:OWZ12869.1};
KW Transferase {ECO:0000313|EMBL:OWZ12869.1}.
FT DOMAIN 25..122
FT /note="Reverse transcriptase RNase H-like"
FT /evidence="ECO:0000259|Pfam:PF17917"
FT DOMAIN 190..298
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
FT DOMAIN 427..481
FT /note="Integrase zinc-binding"
FT /evidence="ECO:0000259|Pfam:PF17921"
FT REGION 478..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 60566 MW; 828B8BC596F963F3 CRC64;
MTKAKQAFEI LKRKIVSTPV LRHPDRTKPF VIITHANQWA ACAVLGQEHD GLIQPVRFTV
RVLHDAGLRY HIAEKEVIAG LRVLQVFRTL IQDCPLIVYT RHSVLKWIMK SKTADGRCVP
WGVLQWHQDV RKIQRDVDGL AVILGGGITP REHLDEVTEE LIPAKGRAKP PPIISVEMLE
DTFQCIVLSF DGAAKTSTRQ GSCGCILWEL PGWKILDAQG FILEDVTVNA AEYCGLLNGL
TMAQTRGVRD LIAVDDSRIV TQHQKRLASC EALKAKFDSV RLVHVKQDFN QAADYLTSKT
LLFGRSWSVQ EDGECQHLER VSKIQEKLMK SAEVHLVSSE PLDPLDYQRE MWRRIKVHQE
QDEYLCDLRD FLNGEVDRFT LHLLRKIAKV ADLFALDARG VLYRLAQSTR GRSRDAQDEL
RLVVLVTLRE DILHYAHEDF QGGHQGIKRT HEKLRYEFYW PGMYADVERH VKECVDCASG
KGHPSNPGPS PGNIEPRRPF EVVSMDFVTH MPKSERGNTF LLLFQDMFQD S
//
