ID A0A225WAK3_9STRA Unreviewed; 948 AA.
AC A0A225WAK3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Calcium-activated potassium channel subunit alpha-1 {ECO:0000313|EMBL:OWZ14766.1};
GN ORFNames=PHMEG_00011706 {ECO:0000313|EMBL:OWZ14766.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ14766.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ14766.1}.
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DR EMBL; NBNE01001267; OWZ14766.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225WAK3; -.
DR STRING; 4795.A0A225WAK3; -.
DR EnsemblProtists; OWZ14766; OWZ14766; PHMEG_00011706.
DR OrthoDB; 71783at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000313|EMBL:OWZ14766.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 323..420
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 470..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 103849 MW; 30A99421D580E9E6 CRC64;
MPFSLWITDI VCAGLFAVDF LFRGIYLSGR RRDYMFSFPG LVTLAVVLPV LPASFFLEYH
TLWFGISDWR FIYPLRFLVC YVEAKAVLSR CHGLMSPVQL FATLCYLQLT IIIAVAAGVI
QIAETADSKY ANGDLGEWTF FNAFFNSVLA FVTIQSPPAD NNLAKVCVGA LVLVLILVVP
YQVSQILALG SSFSPYELAS HTPIPKVFHD DHDLVDINVV VLSEEEPATS LIALLMDPFF
EKRVSFIQGS LLDVDDSQRA ACSSADAIFI LARRVAGESP ANSDHRALMR ILAARREAPK
ARVFAQLHLS SNRGLMTDLG VSNVLCFSEV MHSLLGQNCV CPGFSTFMYS LTSTSSYDTS
GDYDEPPEAD ASWEDRYLHG SSHEVYAVDL PSASVVYGKT FSEVASLAYA QCSGVIVFAI
TTAQSAGCKL LLNPGDSYTC VGQETVFVIA RDQREASAVT NMQACATMPD AWTSQRQRSK
SRHLSRGGSA KIKLASTTGS SAGNDTPSSL GDYEVSSPHR RQSRLVNWQA ESTSPSSTFT
QENQGAWKVT DDDDDPLTVK TSDLTTLDEL TTTSADAAVV QNVTSLQFDI GHIVVCILSP
SSFPHHLEYL IGPLRVRALR QHRPVVIVTT TLPEVEDYEH FQQFDGVHFV VGDPFRHSTL
RRAGIYDAFR IVLMGAEGEV SDAGTSELLQ DAACIALHKT IMTIIGPTQA PRIITELVNR
ANVHFVAQNL AVSGWFPLSE CDSASASTSS LELARNFAVS PAFAAGLTYS TSLCDSLLIN
QFFNSRIKNI LREFIFASWT EGGVGTLPSS PATAGGFETS PTHSTSFGVG VQRSSLFAVE
VPMDFVGRTF EFVFHYLLSS DAILVIGLYR CRPDAMLQPS SIHLLKEGQW VNETKTAPRA
RIEVPESERS VPFGYVYVNP QPHEILTRND LLYVLSDIQP CWADADKD
//
