ID A0A225WI42_9STRA Unreviewed; 472 AA.
AC A0A225WI42;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:OWZ17391.1};
GN ORFNames=PHMEG_0008677 {ECO:0000313|EMBL:OWZ17391.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ17391.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ17391.1}.
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DR EMBL; NBNE01000761; OWZ17391.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225WI42; -.
DR EnsemblProtists; OWZ17391; OWZ17391; PHMEG_0008677.
DR OrthoDB; 49911at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:OWZ17391.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:OWZ17391.1};
KW Transferase {ECO:0000313|EMBL:OWZ17391.1}.
FT DOMAIN 80..183
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
FT DOMAIN 355..406
FT /note="Integrase zinc-binding"
FT /evidence="ECO:0000259|Pfam:PF17921"
FT REGION 211..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 472 AA; 53159 MW; DEBA76ADD04C9EFF CRC64;
MWTVTNSSAY TGKVSLHFRY GQLVVNGWTL AAILGAGITP REHLDEVAEN LIPAKGRIKA
PPSISVDMLD SDFEGYVLSF DGAAKVSARQ GSCGCNLWRL PGWQVLSAHG FHLDDVVVND
AEYHGFIKGL ELAVNRGFRD VVVVGDSRIV IQQAQGLIGC HQPKLQRRLA EYEALKVKFG
STTKTLALGE AWVVEDADEL MHMKFISRIP EKTMKTPETS EQKDDATQSL KRDRPNDLVS
DPVPNASEAI TPVKMVTTRN PSRQVAQVDD PSRPLDYRDE RWRRIKVHQD EDPELKRLKD
YLIGDLLNYT RKDVKIIAKG SDRYVLDSRD VLYRLAAPTP ERPGDKRSEL RLIEPEALRP
DILHHAHEDF QSGHQGITRT YERLRSEFFW TGMFVKECTD CASAKRRPQN PGPSPGDIEL
SGPFEVVSMD FFTHLPKSKR GNTFLLLFQD MFTGYVMCKP MSSTTAQDCA ET
//
