ID A0A225WKY6_9STRA Unreviewed; 569 AA.
AC A0A225WKY6;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=PHMEG_0007538 {ECO:0000313|EMBL:OWZ18386.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ18386.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ18386.1}.
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DR EMBL; NBNE01000596; OWZ18386.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225WKY6; -.
DR STRING; 4795.A0A225WKY6; -.
DR EnsemblProtists; OWZ18386; OWZ18386; PHMEG_0007538.
DR OrthoDB; 46839at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 326..435
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 569 AA; 64364 MW; FEE5B395DAE5C71F CRC64;
MIWALLSIAA LTLSAVSAAL LVFKFYRDWD VRASSVQWLF GIFFTYQTIG AVSRLIYLVW
LTVIIEETSV PTRDLNNGQA IVGPELYRLG VGAVLKLGPR QKNWVTATII VGDTTQFGLA
IWCLLLMYEL SKLVARSMDR GDQHERAKIR LYAYIGHICI VIFLVGEIVL ALIFKCYSKY
AYIILLGVFM LNIAVLIYMI TMVVLLKVKG RKYESVHGRF VASPLYRRLK WIMLVYALFA
FHFHSMSIAM YAAPRRTKQL SSYSGLSFVL FYLRGFLLSI AAGCSQPCIM RCLRPCIPDN
VMVDYTQRRE QVTIPCDWEA PFIKPVFVFT DIESSSALWG IDDGRIMQQA TQIHDDILRN
LLAPYRGYEI TTAGDSFQLA FHTIQEAAEY CLAVQLQLHN AKWPKRLHGL VPATCKVRCG
SRTIFRGLRV RMGIHDTCNS EGSLIRDVHA VTRKVIYTGA SEVIANEIGD LGAGGQIVVT
KRIAEWLAEN SSQLTIDFVV EPVCNGYSIP RLNVVLDVFQ VLPKRMATRS ESFNPPQHVI
QIEQDASPIQ SDIQMHYTLI QTPRQITHL
//
