ID   A0A225WN39_9STRA        Unreviewed;      1463 AA.
AC   A0A225WN39;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Intron-binding protein aquarius {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PHMEG_0006768 {ECO:0000313|EMBL:OWZ19043.1};
OS   Phytophthora megakarya.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ19043.1, ECO:0000313|Proteomes:UP000198211};
RN   [1] {ECO:0000313|Proteomes:UP000198211}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA   Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA   Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT   "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT   of cacao black pod achieved similar genome size and gene model numbers by
RT   different mechanisms.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWZ19043.1}.
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DR   EMBL; NBNE01000496; OWZ19043.1; -; Genomic_DNA.
DR   STRING; 4795.A0A225WN39; -.
DR   EnsemblProtists; OWZ19043; OWZ19043; PHMEG_0006768.
DR   OrthoDB; 7041at2759; -.
DR   Proteomes; UP000198211; Unassembled WGS sequence.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR048966; Aquarius_b-barrel.
DR   InterPro; IPR032174; Aquarius_N.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF5; RNA HELICASE AQUARIUS; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF16399; Aquarius_N_1st; 1.
DR   Pfam; PF21143; Aquarius_N_2nd; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198211}.
FT   DOMAIN          66..448
FT                   /note="RNA helicase aquarius N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16399"
FT   DOMAIN          573..735
FT                   /note="RNA helicase aquarius beta-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF21143"
FT   DOMAIN          872..1186
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          1196..1391
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
SQ   SEQUENCE   1463 AA;  163614 MW;  2A5F967808C5996D CRC64;
     MPRRASTPSS ASHTARELAA NVLKQKPSKQ ALDAIATLYA EFLGDTSDDQ KTLEFATLYA
     EFLGDTSDDQ KTLECLRELD TLRFLEDALW PLADVVESVH DCRHHVKKAW LVSVLLLVGF
     RAREDHSSSL WTFLKPEDTA WKTFMTTLWT ILAETDADDD KWTLKEQTAL TQFLIVCFQS
     LDVPQVAASV LQMTSLPLWT ALSPSQRALE FQTYPKLERH WERIMTTTAK EKKTPKRRKL
     EPKMETPRHE QTALVHRINE FFQVLKTPLD EDTTKEEVVL RLRYVAMFLT LLIDLLSQLP
     TRRFLLTVLR RRHVRTALRN SVLVQHALQS QSANDRQALS KQLAMLDACM RFPIDAHTGT
     SYSPREHREQ RSRHIQTLQQ RVFQSYRNSR VEELAIAPCG HIADPSSFTE MLNAIVGADR
     TQLESLAITV GVLADQDEAD TTSDAELVEV FKEEYSVGSS NEHGAIVSNV PVYPTELDIW
     NELVDCKDGS GTPSDGNELE AVNNATKDIF SADDANLFPL LPVRKLGLQF LNLADYLQRN
     YELFRMEAAK DIRGDLEVAI KHVDAVRALR SYSDNDTIFR GFSRAAVPLA GALQIVKVGK
     PALGQMAPAS VIAQVEVELS DHRHDRKLFD CYQTKEVVFL LTVKATADEG AEMMGFQKQD
     KDTGSFPEDF GVQYVRAAEI IEVMDGGENA INDENPVGKG SKRVFKLALD GMQYKKDLED
     GHLEAYEQVN LLVRRNPRDN NFKAVLDTVA GAWHDSNKEE LLPMWLHDLF LGYGDPAAAM
     YKSIYKARAE KQLVVPMDDL LLDGEHAVEA GGAEKLVDAD DETKELNSKN VSAPFTYVED
     MRDGTTFIRA NHKRGSSTPP STIVSSLRYT KAQVAAVRQG LCDGLTVVVG PPGTGKTDVA
     VQLVLNLYRT TPVREKILIV AHSNQALNDF FAKILSRNAI HEAEIVRMGQ AQIANEGYGA
     GVQGDFSRNG RVTFLLERRA ALLTEVKQMA QWLMKRDPVL YAGLGGGSAS YSCENALIFY
     QFHMKAFLDA TREATKLPAK DDKVVAFSEF FTLRKATAPE NVESLNQFAA DIESYFAELR
     RLQPFELLQT QRQRGDMYLT HHARIVAMTC THAALNHRNL TDLGLTFGSL IMEEAGQVSE
     LNSLIPLLLT CSEKTGSTTS ESKTSSGLKR VVLMGDVKQL PPVVMSPALK TYAHFDQSLF
     TRLLRLGVPH VVLDRQGRSR SELADIYRWR YDGMSSNEET KLGDLPCVDS EPAYQTGNAG
     FSHVAQFVDL SGVSKERQPK PFAYENEEEA RFVVALFRYM MGIGYRSEQV TILTTYNAQK
     ELLQRLLRAD TPDDAKICKV STVDRFQGQQ NDFVLVSTVR SGARVGHLRD VRRATTAFSR
     ARLGLYVVGC RSTLEQARDL QPFLSKLVAI AEKHDGDKAT KLALVPSGQV TTSKAKKTKS
     KKSNVVYISD SKQLEKVVAG LKA
//