ID A0A225WPM3_9STRA Unreviewed; 1843 AA.
AC A0A225WPM3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Formin like protein {ECO:0000313|EMBL:OWZ19581.1};
GN ORFNames=PHMEG_0006144 {ECO:0000313|EMBL:OWZ19581.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ19581.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ19581.1}.
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DR EMBL; NBNE01000425; OWZ19581.1; -; Genomic_DNA.
DR STRING; 4795.A0A225WPM3; -.
DR EnsemblProtists; OWZ19581; OWZ19581; PHMEG_0006144.
DR OrthoDB; 5491073at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0071203; C:WASH complex; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR InterPro; IPR027649; Inf2.
DR InterPro; IPR019309; WASHC3.
DR PANTHER; PTHR46345:SF8; FORMIN 3, ISOFORM B; 1.
DR PANTHER; PTHR46345; INVERTED FORMIN-2; 1.
DR Pfam; PF10152; CCDC53; 8.
DR Pfam; PF06367; Drf_FH3; 2.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211}.
FT DOMAIN 213..582
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 1301..1753
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1730..1752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1785..1843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 630..657
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 12..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1797..1831
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1843 AA; 204920 MW; 3348E9C0C3231230 CRC64;
MWRKRRGSLG GNTPRESPNP MHSHSLTSTP SMSITSSSPF FGSDPNANDR ALVFRLEVPK
PGPLGLDLRA RHIERDKPQR GAVVKGFRPL QGGDVGYVES TGRVKVGDIL QIIHKTPIDD
MPFEQIVKHA MQLQKDPTAW PLAMEFRREP EKQEREPSTA SKPRRNSFFR SSISMSNPVQ
DGNFNEKLQY FRDFFATRIP TGGAAPKEKG KPPKPPKWDT VDEMYRELMS KRGVPEDVMD
ELIRIESLET KWHVVWYAQQ NDLEDNTKSN ATEAEKFAEN LVELKWGNKG LKDLEALRAK
IGIASTDWLE VFLAHFGLDY LTMKLPDPSP FPIEHSKYEK ATRVCEVILR ILRSLTHFTA
GVEAITNTPG LVKRVALCFH TDNGDVKKYT LQLLGIVCYN SAAGHTAVIE AFGHYKETKG
EAIRFSCLRD ALKSTRYSLV FKEDVLSFVN IIVNKAIRLE DRLAIRSDFM ALKMAGYFEE
IRAKSLAVQR TKYPLASSAS TVTEESSSGF PSPVPGAPAT PSPIPNKHIA KNTPSPVLSG
RSAESPLPGR GKDPGTPVGR LDSLKALGGR RSSITRSADD QIGGRLSASK SAPPSPIDRE
PGALSPDGAI VRSSLPTEYK GVSRFGTGGN SIISSSVTQL RNQLDNMEKQ IDVFEQFMED
DRKDTIYEQT DLASVDSVYR SLFDSVTNDP ELQACFLSIL QQLLFIPGDR VIGKEMWALS
EKVMKQITLL APVEEVRNFE LGYDDRKTLL KMRDRYAQFL QKCADEDPTF QFRMGPIILI
ENKDRDNDEL LSDVTADETD EEDAFSSVAA HEHPELMKYF KLLNMGMPMQ HVQLKMSSEI
QTFDPSILET PDKVIQLSKP EEKKGTRAEE HEKFAKFFKL KKMGMPMPHI QSKMSAEGLD
SSILETPDLL LDDDGNELTH SLAGTGFAGI PVKDHDKFAK FFKLLKMGMP LEHVQLKASS
EGLDASLLSK PDQLLDEEGR IFIPGQSKEG PKGIPVKEHE KFAKFFKLMK MGMPLEHIKL
KASAEGLDGE LLSTPDALVN EDGSKFVVGA DVVKGVPVRE HEKFAKFFKL MKMGMPLEHI
KLKVSAEGLD GELLSTPDVL VDEDGKKVEA SAEQHRGVPV KEHEKFAKFF KLLKMGMPMD
HVKLKASSEG LDANLLETPD RLVDADGKEY KGDTPAVKGV PVKEHEKFAK FFKLMKMGMP
LPHIKLKAAS EGLDADLLDT PDKLVDEDGK EIKADGGKTV KASEHPSYAK YFKLLKMGMP
RPQLELKMCA ESLDPKVLET PDAMIPEDLS VAGVAKAPVK PVVAGPPKPK LRNLYWEAVK
TEETAGTIWE KFAKEDEKKA EESAAPAGPP SVADLFAARG KGQQPKSAVS KKDKVLDKFV
DQLSDIFVNK PPKAKESEAK KPMKRRAPTR VALIDAKRAN NIGIMLARFR LPYYKLRNAV
LLVDKKLLSV ERVSALLQFA PEDEELDAVR GYTGDPKLLG DAEQYFREMI CVPRLTTRLQ
AIHATWQFDA YVEEQRKLME SVSNACQELQ ACEALKEIFR VVLSLGNALN DGTSRGGAKG
FRLNILLKLN QVKAADNSIN LLNYVAKVLR AKDPAILEFD KSLPSIESAS RVTTQVLKAG
ESAVRKAANL ICNELEVHAK LPEKEYPQPD PVPGSDEEPE KITDRFQEVI KPFADNAKKS
SEQIADGLES MTKRFEETAS FYGEDPSSPD CGPDSFFSIF YSFAKVLQSA DRDNERKRIA
EERRIRREEE TKKRLEQLKL KKKKSSFATL KTGDVDDIVS KIRAKRSEEK RREMQANGSA
PPSSTGSNRG SGSAPRNANN SSSTQTAAAP RASEVPTPAM EAV
//
