ID A0A225WSV1_9STRA Unreviewed; 1280 AA.
AC A0A225WSV1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=TKL protein kinase {ECO:0000313|EMBL:OWZ20655.1};
GN ORFNames=PHMEG_0004903 {ECO:0000313|EMBL:OWZ20655.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ20655.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ20655.1}.
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DR EMBL; NBNE01000302; OWZ20655.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225WSV1; -.
DR STRING; 4795.A0A225WSV1; -.
DR EnsemblProtists; OWZ20655; OWZ20655; PHMEG_0004903.
DR OrthoDB; 70541at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 7.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001995; Peptidase_A2_cat.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 6.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 25.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 18.
DR PROSITE; PS50088; ANK_REPEAT; 20.
DR PROSITE; PS50175; ASP_PROT_RETROV; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Kinase {ECO:0000313|EMBL:OWZ20655.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:OWZ20655.1}.
FT REPEAT 35..67
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 68..101
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 102..134
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 135..167
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 201..233
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 234..266
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 267..299
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 357..389
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 390..422
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 423..455
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 456..488
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 490..522
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 523..555
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 589..621
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 622..654
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 655..687
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 701..733
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 734..766
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 767..799
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 802..834
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 819..836
FT /note="Peptidase A2"
FT /evidence="ECO:0000259|PROSITE:PS50175"
FT DOMAIN 884..1130
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 1280 AA; 140534 MW; E4E1663F5AB24F46 CRC64;
MAEVTPFLVA VGEGDVERIS ALVEGGEDVN QLGSRQETAL MRAAGDGNLA VVRFLIDAGA
DVEAVHWMGN TALINAVWRK GNLNVVKILV ECGADVNVSD SWGDTPLIYA ARNGDLEVIK
FLVEVGAQVN ALGSKQRTAL LCAIRNGHLN TARFLLENGA EIEAADYNGW TSLFHAVWIE
NEAIVQLLVE EKAIVDTMDR SNLTPLMYAV LKDNLKISKF LVKNGANIQI VNNEGSTALI
YAARNNNLEI IKILVECGAY VNAVNSAKMT PLVYVLECGD MTAVRFLIES GADTKAVNLN
NTVENKKLDD FRSLVDSVDD TKTKNVTMLI NAIENGDLDF VQQHFGKDSD RNAANMFGRS
LLICAAEIGI LDIVRILIDH GADVNTRDRH SRTPLLHASK NRNWDLVRIF VSRGADVNAA
DNDGLISLMV AAQNGNMDIV QYLVERGADV NTVDQRERTA VLYASMGGYW DVVRFLVSSG
ADVNAVNIDD RSTALIYAAK QGQLETIRIL VANGADVNAA DCQNLTSVMI AAETENLRVV
CFLIDSGAEI ASLENKKIKL LMRTAESCDL KGVRLLLGDG SETNIVEVFG RTLLMCAAKT
GRSDILQFLL ESGADVNAVD RRYRTPVLHA SENRHWDVVR FLVGKGANVN AIGKSGWTSL
LYAVQENHLD IIQFLVDAGA DINTSTTNWP TSLLNAASGN NKRIPLIVAT DKGVLEVVQF
LVQRGADVNS VGSDGQTALM QAAEKGNFKT IKFLSQSGAE FDVADKNGKT VLMCAVMSGD
LDALQFIYEK NSDVDVNAVD HNGWTSLMYG AQSGNLDVVK FLLDSGADVS IVNNNHRTAI
FIASSRGYTD VQHLLMEYLP YTQATMGNPI SQMPDNCFIP ALDVELQEFI GSENVGRKYR
ALWLDAEVVV KLFVPELYVT TFSHEVAAWH RLRHPHVLQL YGACDIGHNF FVCEWASNGS
LVEYLSACKK RGERQTPWKF LHEAALGLAY LHERKIMHGN LCNNSILVGG DGMVKLANFQ
VSGSATWEQS DVGCWQAPER LRGDATSIAS DIYSLGLCII ATVTRETPWR GCLDDISKVR
KANWNATADP VKYGPVDDMT DDLTLLASKM CGNDPASRLS SIEAQGHSMT AIYRRIETIW
YAIDVTNAEE YKKRQEEKRI KLQESFISGV SKTLIVLDEL ETAEARETFV AFLKAEIDSH
GSSYSAKTLS VLEKAYVDFY TGLKSDAVTV MPKWFLPWYE LAFDGMNYLG EGGFGEVYRA
KWLESEGVVK QVKLTNSTKL
//
