ID A0A225X0T0_9STRA Unreviewed; 1002 AA.
AC A0A225X0T0;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|PROSITE:PS50050};
GN ORFNames=PHMEG_0001335 {ECO:0000313|EMBL:OWZ23735.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ23735.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ23735.1}.
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DR EMBL; NBNE01000047; OWZ23735.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225X0T0; -.
DR EnsemblProtists; OWZ23735; OWZ23735; PHMEG_0001335.
DR OrthoDB; 66446at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR CDD; cd00185; TNFRSF; 1.
DR Gene3D; 2.60.40.2030; -; 4.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR PANTHER; PTHR11878:SF65; NA_CA-EXCHANGE PROTEIN, ISOFORM G; 1.
DR PANTHER; PTHR11878; SODIUM/CALCIUM EXCHANGER; 1.
DR Pfam; PF03160; Calx-beta; 4.
DR Pfam; PF00020; TNFR_c6; 1.
DR SMART; SM00237; Calx_beta; 4.
DR SMART; SM00208; TNFR; 2.
DR SUPFAM; SSF141072; CalX-like; 4.
DR PROSITE; PS50050; TNFR_NGFR_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 817..860
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 817..860
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 865..908
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 865..908
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 839..852
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 842..860
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 887..900
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 890..908
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 1002 AA; 107372 MW; A8F94F646C83EE50 CRC64;
MISRPIIEIF DALRGAEAVA NGRFQFAQDV YSTTEELGVA AITVQRSLGS DGRAAVYVSS
IPGVGNAVVG RDFKPIFNVS LVWQDGEDAE KALYLPIYND GKPQEIAKTF TLKLHDAIGA
EINLNRNKTQ IILEPPANLV PGSFSFNNSA VTIAEGNTLT VPVLWIAGTT STASVKFEIV
CKTACSPGDF TLVSPTTMLL KWKRDDNPNS TTRVQNIVLK ILDDNFYEQA ENFVIRLGTV
EAAANAVIGT GTIGDNGEMV VTIAGPNNVQ SGTLQFDADC FDCASTKYSV IAGGSALVVI
KRRRGSDGNC SVTIATQDDT AIAGLDYELL ETTVSWKEGD TSDRQIIMKS LARADPRLPT
RRVTLILRNN HGASITGIQA NTTYVNITSP VNAVLGDINF AAREPLEFVL RNPDLSFIEL
ASRNTSSRLQ LCPRVVVSKP GVLSVAIQRN FEAFVVSVSV IVDTVAGTAT SGVDFEPLTN
TVVSWANEDS DVKQVLVKIL TPPTYDPNPR SFRLQLSDAR GAIVGNCDTL EVSLTRIAQG
PHVISFDLDM VFGTLTLRMS TSVQSSTLDV TKLLLQSASE QLNGPTFRFN ALQTTTSSLD
GTTIVLNIGA GDLNSLKRVV GLAQTATTTF LSVDKGLFQY VLNSCQSSGI FACSPDKTVA
STAIAVDKFT ADTVAPVLVG YSLDLPRRLL KLHFSEGVNF SSLTIEALSL SDTATGFNIY
RLSSSTTRLF SPQPDPLSGA TMRDANRLPA DYTFLTLQLG RTDVTALSSI GSGKIGIVRS
STFLGMGSTF VADYTGNAVK IIGPPKLLQV AAADCSVCPT GTYLTSSCSD LKDRKCAPCS
VCPNNSFALE ACRATQDTLC FPCTECRSGQ FVSVACSPTT DRVCAPCTQC TLDEYEVSSC
VAGTDRICRT CNSCVLTPAQ QTLCQRSPIW KRIQMRMPFS CPQPGQQFKT REEQLQRAKS
NKCGSGRCSC IATGIPGNSN PTGDGFPDDS RCTGHVVYNI FV
//
