ID A0A225X1Z4_9STRA Unreviewed; 129 AA.
AC A0A225X1Z4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 22-FEB-2023, entry version 16.
DE RecName: Full=GTP-binding nuclear protein {ECO:0000256|RuleBase:RU363057};
GN ORFNames=PHMEG_0001375 {ECO:0000313|EMBL:OWZ23692.1};
OS Phytophthora megakarya.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4795 {ECO:0000313|EMBL:OWZ23692.1, ECO:0000313|Proteomes:UP000198211};
RN [1] {ECO:0000313|Proteomes:UP000198211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=zdho120 {ECO:0000313|Proteomes:UP000198211};
RA Ali S., Shao J., Larry D.J., Kronmiller B., Shen D., Strem M.D.,
RA Melnick R.L., Guiltinan M.J., Tyler B.M., Meinhardt L.W., Bailey B.A.;
RT "Phytopthora megakarya and P. palmivora, two closely related causual agents
RT of cacao black pod achieved similar genome size and gene model numbers by
RT different mechanisms.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: GTP-binding protein involved in nucleocytoplasmic transport.
CC Required for the import of protein into the nucleus and also for RNA
CC export. Involved in chromatin condensation and control of cell cycle.
CC {ECO:0000256|RuleBase:RU363057}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU363057}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Ran family.
CC {ECO:0000256|RuleBase:RU363057}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ23692.1}.
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DR EMBL; NBNE01000049; OWZ23692.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A225X1Z4; -.
DR STRING; 4795.A0A225X1Z4; -.
DR EnsemblProtists; OWZ23692; OWZ23692; PHMEG_0001375.
DR OrthoDB; 5471873at2759; -.
DR Proteomes; UP000198211; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002041; Ran_GTPase.
DR InterPro; IPR001806; Small_GTPase.
DR PANTHER; PTHR24071:SF0; GTP-BINDING NUCLEAR PROTEIN RAN; 1.
DR PANTHER; PTHR24071; RAN GTPASE; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00627; GTPRANTC4.
DR SMART; SM00176; RAN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51418; RAN; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU363057};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363057};
KW Nucleus {ECO:0000256|RuleBase:RU363057};
KW Protein transport {ECO:0000256|RuleBase:RU363057};
KW Reference proteome {ECO:0000313|Proteomes:UP000198211};
KW Transport {ECO:0000256|RuleBase:RU363057}.
SQ SEQUENCE 129 AA; 14818 MW; 6F7CBE0F190DB30E CRC64;
MFDVTSRITY KNVPNWHRDL FRVCENIPIV LCGNKVEVKD RKVKAKQITF HRKKNLQYFD
ISAKSNYQFE KPFLWLARKL VGDNNLTFVE APALRPPEVT ITQEQIAQIE ADASSAAAAV
PLPDEDEDL
//
