ID A0A226BZ24_9FIRM Unreviewed; 684 AA.
AC A0A226BZ24;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:OWZ84246.1};
GN ORFNames=CDO51_04095 {ECO:0000313|EMBL:OWZ84246.1};
OS Natranaerobius trueperi.
OC Bacteria; Bacillota; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC Natranaerobius.
OX NCBI_TaxID=759412 {ECO:0000313|EMBL:OWZ84246.1, ECO:0000313|Proteomes:UP000214588};
RN [1] {ECO:0000313|EMBL:OWZ84246.1, ECO:0000313|Proteomes:UP000214588}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18760 {ECO:0000313|EMBL:OWZ84246.1,
RC ECO:0000313|Proteomes:UP000214588};
RA Zhao B.;
RT "Draft Genome Sequence of Natranaerobius trueperi halophilic,
RT alkalithermophilic bacteria from soda lakes.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ84246.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NIQC01000006; OWZ84246.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226BZ24; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000214588; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:OWZ84246.1};
KW Cilium {ECO:0000313|EMBL:OWZ84246.1};
KW Flagellum {ECO:0000313|EMBL:OWZ84246.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000214588};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 57..76
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 96..119
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 188..210
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 684 AA; 75488 MW; 068005C690E1676A CRC64;
MRHGDLIFVL AVIAIVLMLI LPVPPELLNI LLVVNITLAL TILLVSMYTL EPLQFSIFPT
LLLLITIYRL ALNVSSTRLI LLNADAGEVI QQFGEFVVGG NALVGFVIFL ILVAIQFIVI
TKGAERVSEV TARFTLDAMP GKQMAIDADL NSGLINEEQA RERRKAVEQE ADFYGAMDGA
SKFVKGDAIA GIVITVINVL GGFVIGMAQQ GLTFQESLQT FTLLTVGDGL VTQIPALLIS
TSTGIVVTRA ASDSNLGEDV ISQILAHPKV LFIVAGVLAM VGILPGMPPL PFLLLGLIMA
ILAYHIKTTV IEKVPSPEEE EVAAKEEEAE GYRSPENVMS LLQIDPIEFE FGYGLLPLAD
PDQGGDLLDR VTMIRRQVAL ELGIVVPVIR VRDNIQLSSN EYCIKIKGVE VAREEVLPNH
YLVMIPGDEK PEDLDIVGTQ TKEPVFNLPA MWIDEDQREH TEMSGYTVVD PPSVLATHLT
EIIKRHAHEL LGRQEVKELV ENLKESYPAV VEELVDNVLS LGEVRNVLSN LLKEGVSIRN
LLTIAETLTD YGAITKDTDM LTEYVRQNLS REITNKLKEL QGDSLKVITL SPELEQKLSE
SIKQTDHGNY LSIEPQITQK IQKQLQNYYE QLNEQGIHPI VITSPMVRLY FKRLTEGVFT
NLTVVSYHEL EPQVEAQSVG VVSI
//
