ID A0A226C1B4_9FIRM Unreviewed; 719 AA.
AC A0A226C1B4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Histidine kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CDO51_00775 {ECO:0000313|EMBL:OWZ84971.1};
OS Natranaerobius trueperi.
OC Bacteria; Bacillota; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC Natranaerobius.
OX NCBI_TaxID=759412 {ECO:0000313|EMBL:OWZ84971.1, ECO:0000313|Proteomes:UP000214588};
RN [1] {ECO:0000313|EMBL:OWZ84971.1, ECO:0000313|Proteomes:UP000214588}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18760 {ECO:0000313|EMBL:OWZ84971.1,
RC ECO:0000313|Proteomes:UP000214588};
RA Zhao B.;
RT "Draft Genome Sequence of Natranaerobius trueperi halophilic,
RT alkalithermophilic bacteria from soda lakes.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWZ84971.1}.
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DR EMBL; NIQC01000001; OWZ84971.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226C1B4; -.
DR OrthoDB; 9798833at2; -.
DR Proteomes; UP000214588; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000214588};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 128..182
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 195..247
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 248..322
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 405..533
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 526..719
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 719 AA; 82656 MW; F2E462E78D794924 CRC64;
MYLFKKSDST KLALIAIGAI IIIISVLLEF FSFPYVTISG GILTIYSAIW FGVRGGFSIS
LFSCFIILIY YFVNPDQYIL SNVITSFFFY LFLGVIVGLF HDRLKESQKQ LIAAQISQRN
VEKSLEEERN RFKQYLDIAG VMLLAVDSDG KVTYINQKGC DLLGCNFEDI IGENWFERFF
PDVDDKNFIN SDKFSELESY VLTYNQQKRL FHFRNTKLTD SEGNIEGILS SAEDITDRRQ
TENDLKGSEE KFRNLAENIP GVIYLCHYDK SYSMIYLNQD IESLTGYDKS DFLEGKLNLT
DLILEKDLDT INKQVTRAIE NQKPFYLIYR IKDVLGQIKW LEEKGIGVYK EGKLNHLEGH
ISDITARKEA EERIRFLSFY DELTGLYNRR FFNEELYRLD TVRQLPLSII LGDVNGLKLI
NDTFGHFEGD KLLLKAAEAF RESCRKEDVI ARFGGDEFIV LLPKTTIEEA NNIANRIEDN
MKQKQLSHIP PSMSLGVATK DLAHISVHQL IKEAEDKMYE KKLLKSKQVR SDILQSLLKT
LREKSYETER HSKRLEVLSV KIGEALNLPL SELQKLSILA KLHDIGKVTI ARTILKKKTS
LTTEEWKTIK KHPETGYKIA LSAPEIAPIA ECILYHHERW DGQGYPHGIE GDEIPLLSRI
IAIVDSYDVM VSGRCYKKSM PKESAFKEIE RCSGRQFDPN LARVFIDIMK EGTKLDTIS
//
