ID A0A226D168_FOLCA Unreviewed; 1406 AA.
AC A0A226D168;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=Fcan01_26843 {ECO:0000313|EMBL:OXA38457.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA38457.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA38457.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA38457.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA38457.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA38457.1}.
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DR EMBL; LNIX01000046; OXA38457.1; -; Genomic_DNA.
DR OMA; CAMASNI; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47642; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR47642:SF2; PHD-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05970; PIF1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044, ECO:0000313|EMBL:OXA38457.1};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287}.
SQ SEQUENCE 1406 AA; 159853 MW; B88A8E4BC227D9C7 CRC64;
MVTSTLAFKD PIEPSQVDTD EENAAAISIN ICVEGEAQES VSDRSNVGAD ETLIFRRNSL
DIYGIRIAPA EGNIPIPMHR DLNAELLSFP TIYAGVPPSF KKWVRVTYTD IARTEIRRYD
RRACRPTKLL YAFKRSFNEK VVNAVQICMR KKIGTRHVTA GTLTPGFVEN LCKKDDGRCI
LKTSAEAKWT EMIIMLTKLI DGKEITEEEA ADLPFIKVAE LVRSDPVTCM IHFDHKYRAL
LTTLLTQRCA EGKMEKLIGY QLHKHSHTCE KKLKRGQKCR FGFPKPQLPT TMILRPLPSD
WNPQEIKDAE ELYAEIQDKL NQLGRAYKED ICFKNFLVEL NMDYSSYKIA IRSSIKRPTV
FLKRSTNASF INPYNRKLLE AWEANLDIQF LLDIYSSLDQ DVRRGNIAIQ DKLKKFASIL
INGSEISAQE AAAFLQGISN TNCSRSDVFI NTSEPDERIT FLKPKEELEE LGDDSEDICM
KGLNDHYSQR PKELEDICLA EFASMNNFTA LKRKRRWKTR QQETLILKSF MSRFNMITTY
YWEVKQVYLY QVHLLLTAKI STPTKGRKAA NKHELLDGSG TVYKRTIRKI IRFRHYGKQA
DPTNYLREQL MPFVPWRNEK KDFIDVDKVE SASIHQEQLK CNSQPFYFNH DVDDELLQGL
LDDAEERQIE DDDDKVIVVN DKGVDAEDYF NDFRVDDFAP TTSKVEHFLP PRLVDETEYL
KMMRSLNQRQ RRFVLNVLHS LKTGKVPFHN FLSRGEGVGK SHVVTAIAQS FMRYCSKFPN
VNPEQLCVLV AAPTGKAAFN VFGMTLHCTF QLPPTQSAGG LGDLQSGILN TLRIRLEGVK
LFIIDEISMV SVKQLYDVDQ RLRQIYEATS PFGGKSFVVV GHLRQLPPIG GSYVFKLRTH
IPRGAVVGNH LWELFQLYEL TEIMSNVANG SFAKHLIIWL KTNAECQKYN SEVHAKLVSD
GAMSTAHDKI QGSASEADKK RPLEYATTLT APQSDGLPYQ TYLKVGAEYF VGTNVDAQDG
LFNGSTGTLK LIEYSTKAQG KPTRAWLDFH NSMVGMHKSA STRTYQIRKN IDEELVAVDR
ITRNLSRTGR HQGLQIIRTQ VPLVPANGTT IAKSQGSTHI CSVVAVKSYC DDDEPPRKSE
GLFIYGDFTP PSTPGPNDPV SIEMARLRST EFAFSMKFLQ DYGDEVEKIF FQNIQSFNSH
GDDIRADHCA MASNILAFVE PWFLPQDLVD VPGFHCIYRK NCGGPNRNSE RAPIMAKESE
NQLTNIPLLH VEKIGSSHCL FLQWVISGVN VVMVYKSPEF SKSRFLTTLD EILNQLSGNV
LIFEDANINL SKWEGRGLLE LFATKNCTSK PPIQDPSTDY GTHIDICFSN VAEIEAWFYE
SYLSYHKAIC IVWPKPSMNN NNLKNY
//
