ID A0A226D4Q4_FOLCA Unreviewed; 658 AA.
AC A0A226D4Q4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Tudor and KH domain-containing protein {ECO:0000313|EMBL:OXA40522.1};
GN ORFNames=Fcan01_24671 {ECO:0000313|EMBL:OXA40522.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA40522.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA40522.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA40522.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA40522.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA40522.1}.
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DR EMBL; LNIX01000033; OXA40522.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226D4Q4; -.
DR STRING; 158441.A0A226D4Q4; -.
DR OMA; NMVQEMT; -.
DR OrthoDB; 375531at2759; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd00105; KH-I; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22948:SF29; TUDOR DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00013; KH_1; 2.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00322; KH; 2.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50084; KH_TYPE_1; 2.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 463..521
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 38..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 101..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 608..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 72075 MW; 497B6DD20A0CD3B0 CRC64;
MSEPNGLSRA FVSRILFGGA IGAAIGIMYL VYIRQKKKED ASSDASTVTS SLARKKKRVS
SGERNRVTFS DQTEIIVKSP SPQLTKDDME AEDFIPFRVK NEDAPPAQPS PPAQPSSPQI
NKSPTKTEVD SIPPTQKSPP RPAQDKDDSV NKEVSIKQEE PIKSPVVETV TSEEIKPQTS
LPPSQTLSNS VNHAANGHGQ NLKQAITPET DYDRTGITRE LQISRDHVPG LIGKKGTHIR
AIQADSNTII TFKDESLGNG DRICLIRGQP QDVTVAESLI EKYIIEQPIV TSQTMHIPHS
SVGRIIGKGG ENIRSIQDLS RAKVNVDTGN QFHSRGGPDA VRMVLVTLRG TEEQIANARQ
MIIEKVDEEQ SMRRKIDLMT QSRAPRKSAG GGFPTTSANP SAAVNGNHQS TKQSGVLEVF
VSCAYHPNDF WIQVMGHESI DLDKLTESMT EWYSQFPPEP LLGLSAGEII AAPFDVDGKM
YRGKIISLVD DTAEVSYVDY GDRRVIQQSD IRRIHPEFLK LRFQAIQATL NLGCTTGERW
SDDAIVTFCD LTFCAQWKSL TAKVKDYLKG SSDAKETVLW VELLDKDLNI GNELINRGLA
MINDTPQLTY SDTTPRSGSS VASSNGSKKS YASVASVESK VSDDGAKEGP WDDNVNGN
//
