ID   A0A226D5E2_FOLCA        Unreviewed;       418 AA.
AC   A0A226D5E2;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Death domain-containing protein {ECO:0000259|PROSITE:PS50017};
GN   ORFNames=Fcan01_25398 {ECO:0000313|EMBL:OXA39871.1};
OS   Folsomia candida (Springtail).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX   NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA39871.1, ECO:0000313|Proteomes:UP000198287};
RN   [1] {ECO:0000313|EMBL:OXA39871.1, ECO:0000313|Proteomes:UP000198287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VU population {ECO:0000313|EMBL:OXA39871.1,
RC   ECO:0000313|Proteomes:UP000198287};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OXA39871.1};
RA   Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT   "The genome of Folsomia candida.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXA39871.1}.
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DR   EMBL; LNIX01000036; OXA39871.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A226D5E2; -.
DR   Proteomes; UP000198287; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   Pfam; PF00531; Death; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        159..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          26..93
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          121..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   418 AA;  46553 MW;  4408B738744DD0DE CRC64;
     MTLLENISGA VDILAKSIPV ITNLNQLFQA MELPPDKIVD ITRNHYNSIK ERLTVALQAW
     KELVGSRATV EHLVRILLAL QHKDSAEMIQ NSAEALGPTS IPDSTSIIDL EESAALLRGT
     LTNNNASPPQ DVLLPTQEQS TNPEEGQTSQ IFRKVTTGIS LLVIIIMTVL FACYHIIPIR
     VLDKYSSDRP EIVTRTENYP TTPSLSRQHK NECVALRKKG KMRCPINHEI PHQNLRIVTL
     NDNNHHDFCD AEHKGCFLGG NPDNDDFSSD QEFCPHNLVA LEILSAIRRK RLTNFLDRYC
     LLGSLLFGKN ASVEATPGTS YLSDKLNYPS LQSLSFEGTV NVSVILANLS DHVSFPCLVE
     INLSCVILMA EDITSLRNLV ASSGSLRRIN CQDNNFCENL LDVNNGHELN RNFTRTIC
//