ID   A0A226D759_FOLCA        Unreviewed;       523 AA.
AC   A0A226D759;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Lactase-phlorizin hydrolase {ECO:0000313|EMBL:OXA40567.1};
GN   ORFNames=Fcan01_24692 {ECO:0000313|EMBL:OXA40567.1};
OS   Folsomia candida (Springtail).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX   NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA40567.1, ECO:0000313|Proteomes:UP000198287};
RN   [1] {ECO:0000313|EMBL:OXA40567.1, ECO:0000313|Proteomes:UP000198287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VU population {ECO:0000313|EMBL:OXA40567.1,
RC   ECO:0000313|Proteomes:UP000198287};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OXA40567.1};
RA   Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT   "The genome of Folsomia candida.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
CC       {ECO:0000256|RuleBase:RU003690}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXA40567.1}.
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DR   EMBL; LNIX01000033; OXA40567.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A226D759; -.
DR   OMA; IAHEINP; -.
DR   OrthoDB; 3373839at2759; -.
DR   Proteomes; UP000198287; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 1.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:OXA40567.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..523
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012623920"
SQ   SEQUENCE   523 AA;  60211 MW;  EEA85845B9160B7E CRC64;
     MLNSCLFLGA LLLLGFGEEA KSVAPKNQIR ALFPDNFRWG FATASYQIEG GWDADGKGEN
     IWDRFTHTPG NIADNSTGDV ACDSYHNYAR DVEMLKDIGA DYYRFSLSWS RILPNGTLAV
     VSEAGIAYYN NLINLLIANN IEPMITLYHW DLPQPLQDIG GWPNEALIPH FENFARLAYQ
     RFGDRVKLWI TFNEAFVTCM HGYGYGKHAP GISGEDTEPY KCAHTILKSH ARAYRMYYDE
     FFQAQNGRVG ITIDSGWYAP LDPNNPSDVE AAERAVRFKH GWFAWPVFYG HYPDEMRIFV
     DKKSEEEGLD QSRLPEFDRY WETQVKGSWD FLGLNHYTTE LCTYKVGEYS GWSQDQDVGF
     SRDPTWPESA SDWLRSVPWG FGNLLRWIKR NYGNPLVYVT ENGWSDSDAV GLEDDLRVEY
     YTNYTQSMLQ AITEDRCDVR SYTAWSLMDN FEWARGYSER FGVHWVNFTD PARPRIPKKS
     AAFLKQLFAD NGYPGPDVNS SAESKHWKIL SFTYFILIKF MLG
//